1 / 2

Ross Lab - Biophysics

Ross Lab - Biophysics. 10  m. Cytoskeleton: Rich Biological System of Interest Microtubules Shape the Cell Motor Proteins Move Objects and Microtubules Microtubule regulation through modifications and motor proteins Microtubule Motors Traffic Problems Dynein, Kinesin, Eg5, MAPs

ewan
Download Presentation

Ross Lab - Biophysics

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Ross Lab - Biophysics 10 m Cytoskeleton: Rich Biological System of Interest • Microtubules Shape the Cell • Motor Proteins Move Objects and Microtubules • Microtubule regulation through modifications and motor proteins • Microtubule Motors Traffic Problems Dynein, Kinesin, Eg5, MAPs Using Total Internal Reflection Fluorescence (TIRF) Microscopy Optical trapping of motors to measure force • Microtubule Severing Enzymes Katanin, Spastin, Fidgetin Using TIRF microscopy March of Dimes Funded • Microtubule Mechanics Stability, Flexibility, Structural Studies NSF funded Green = Microtubules Blue = DNA Ross, et. al., Biophysical Journal 2008 Website: www.people.umass.edu/rossj Email: rossj@physics.umass.edu

  2. Ross Lab - Biophysics • Biochemistry and Molecular Biology: Protein Design, Purification, and Characterization • Microscopy: Epi-fluorescence, TIRF, electron microscopy, AFM • Analysis: Image analysis, MATLAB analysis, measure velocity, intensity, Fourier modes BioBootCamp 2010

More Related