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Optimizing Control Over TGF-β and PDGF-AA Concentrations in Cell Culture Systems

This study explores strategies to regulate TGF-β and PDGF-AA levels in cell culture. By manipulating various parameters such as time and concentration, researchers aim to achieve precise control over these key growth factors for improved experimental outcomes and cellular behavior. The results shed light on effective methods for influencing cellular responses and pathways within a controlled environment.

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Optimizing Control Over TGF-β and PDGF-AA Concentrations in Cell Culture Systems

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  1. B A LCTC LCTC SF SF * % over control % over control * * * * 5 10 20 40 0.01 0.05 0.1 1.0 TGF- concentration (ng/ml) PDGF AA concentration (ng/ml) C D 3 4 TGF- TGF- No TGF- No TGF- 3 2 DPM (x 10-3) DPM (x 10-3) 2 1 1 LCTC SF 0 0 10 20 30 40 50 0 10 20 30 40 50 Time (hours) Time (hours)

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