GENETICS OF MELANOMA

Jul 07, 2025

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Explore the intricate genetics of melanoma, identifying key mutations and pathways driving its progression. Learn how genetic research can pave the way for personalized therapies and targeted interventions to combat this aggressive skin cancer.

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GENETICS OF MELANOMA

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Melanoma

Melanoma - Outline. General statistics and developmentRisk factors and patient assessementPathology and prognosisWork-up and stagingSurgical treatmentLymph node controversy/sentinel node Adjuvant therapy. Melanoma - Data. Incidence increase fastestMortality increase 2nd only to lung5th most prevalent, incidence 7%/year increase 5% skin cancer, 75% skin cancer death1/75 in 2000, 1/1500 in 193520% H

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Melanoma

Melanoma. Due to its preventable nature and its increasing incidence, the U.S. Surgeon General has labeled melanoma a “public health crisis” 1 - U.S. Surgeon General’s Office. Skin cancer - most commonly diagnosed cancer in the U.S. 2

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Melanoma

Melanoma. Almost 30% of all melanomas arise in the head and neckWidespread use of sunscreen has not lowered the incidence.Incidence is increasing almost 5% per yearApproximately 47,000 new cases in 2001. Predisposing Factors. Sun ExposureAge, frequency, severity of exposure may play a roleSunsc

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Melanoma

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Melanoma

Melanoma. Kari Kendra MD, PhD 9/18/2009. Melanoma Incidence and Mortality. Incidence (US) 59,580 new cases 33,580 new male cases 26,000 new female cases 12 per 100,000 population Mortality (US) 7,770 total 4,910 males 2,860 females.

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MELANOMA

MELANOMA . Melanoma. Melanoma. Represents 4% of all cancers Most common malignancy in women aged 25-29. Incidence is rising faster than any other cancer Lifetime risk of developing melanoma now about 1 in 70 30% arise in existing nevi. Risk Factors. Fair skin Presence of atypical nevi

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Melanoma

Melanoma. Sandy Beam RN, OCN, CCRC Research Nurse Clinician Maryland Melanoma Center Franklin Square Medical Center Baltimore, Maryland . Treatments and therapies “What do you need to know”. SKIN FACTS & FUNCTIONS Largest organ in the body 1 st barrier to protect us from infection and

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Melanoma

Casey Bower. Melanoma . What is Melanoma?.

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MELANOMA

By: Elizabeth Albert. MELANOMA . What is Melanoma?. “ Definition of melanoma : A form of cancer that begins in melanocytes (cells that make the pigment melanin). It may begin in a mole (skin melanoma), but can also begin in other pigmented tissues, such as in the eye or in the intestines. “

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Melanoma

Melanoma. By Blake Mednick. Introduction: Melanoma. Causes the most deaths of all the skin cancers Begins in Melanocytes 1 in 65 people will be diagnosed with melanoma in their life Can appear anywhere on the skin Easy to cure if caught early enough. Causes. Excessive sun exposure

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MELANOMA

MELANOMA. New cases (2007): 3528 (Males 2123; Females 1405) Deaths (2007): 482 (Males 342; Females 140). 1.7x more likely to be diagnosed 3x more likely to die 2 nd for incidence, 7 th for deaths Risk: 1 in 23 men by age 75 1 in 13 men by age 85. 3 rd for incidence, 12 th for deaths

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Melanoma

Melanoma. By Libby Walker, Jessica Morehouse, Rebecca Jurovich, Ashley Leonard. What Is Melanoma, How Do You Get It?. A cancerous disease that infects the skin. Can occur in all layers, depending on the type of melanoma. It is hereditary and can be acquired through UV ray exposure.

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MELANOMA

MELANOMA. RILEY AND EDIE. DEFINITION. MELANOMA IS THE DEADLIEST FORM OF SKIN CANCER, KILLING AROUND 9,700 PEOPLE PER YEAR AND ABOUT 1 PERSON DIES PER HOUR FROM THIS DISEASE. http://www.skinveinclinic.com.au/images/cancer/HIMG079.jpg. WHAT IS IT?.

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Melanoma

Melanoma. Hai Ho, M.D. Department of Family Practice. Epidemiology. Sixth most common cancer Incidence increases from 1/1500 in 1930 to 1/75 in 2000 1% of skin cancer but account for 60% of skin cancer death. Risk factors?. Sun exposure Intermittent intense exposure Childhood

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Melanoma

Melanoma. Melanocytes. When skin is exposed to sunlight, melanocytes produce more pigment, causing the skin to tan. Sometimes, clusters of melanocytes form noncancerous ( benign) growths called moles .

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GENETICS OF MELANOMA

GENETICS OF MELANOMA. Ivana Antigoni Genetica Medica “Sapienza – Università di Roma” Ospedale S. Camillo. Kidney cancer and melanoma: progresses in clinical and translational research Rome, November 23-24, 2007. Genetic susceptibility to Melanoma.

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Melanoma

Melanoma. By Dr Abeer Elsayed Aly Lecturer of medical oncology SECI 19/03/2013. Melanoma Incidence and Mortality. Incidence (US) 59,580 new cases 33,580 new male cases 26,000 new female cases 12 per 100,000 population Mortality (US) 7,770 total 4,910 males 2,860 females.

1.12k views • 92 slides

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