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Toxicity of solvents. suicide attemptdirectly toxicity. Toxicokinetic. Absorption: concentration, time, dose, lipophilicity, blood flowDistribution: the more lipophilic solvents the more toxicityMetabolism: Metabolic inactivation (detoxification) Ex. tolueneMetabolic activation (bioactivation) Ex. benzeneElimination: liver, renal, respiratory.

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