Cloning – In the Eyes of the Beholder Ida Chow, Ph.D. Society for Developmental Biology Bethesda, Maryland Society for Developmental Biology
Ida Chow, Ph.D.
Society for Developmental Biology
The Society for Developmental Biology declares a voluntary five-year moratorium on cloning human beings, where ‘cloning human beings’ is defined as the duplication of an existing or previously existing human being by transferring the nucleus of a differentiated, somatic cell into an enucleated human oocyte, and implanting the resulting product for intrauterine gestation and subsequent birth.Sept. 1997. Extended Jan. 2003
How does a single cell, the fertilized egg, transform into a complex organism, with many different types of cells, tissues and organs?
- control / regulation?
Totipotency– Capable of giving origin to all the cell types in the organism, person, e.g., fertilized egg developing into a whole organism
de-differentiating the adult somatic cell nucleus?
unlimited capability for cellular reproduction
more direct access to stem cells
large number of available stem cells
many identified inducing factors
limited capability for cellular reproduction
difficult access and identification of the stem cells
limited number of available stem cells
National Institutes of Health (http://www.nih.gov ):
Stem Cells: a Primer (http://www.nih.gov/news/stemcell/primer.htm)
Stem Cells: Scientific Progress and Future Research Directions