IACUC EVALUATIONS

1. IACUC EVALUATIONS Program Reviews & Facility Inspections William R. Parlett, Jr., DVM, DACLAM Compliance Officer (Contractor) Office of Laboratory Animal Welfare NIH, DHHS

2. IACUC EVALUATIONS • Program Review • Facility Inspection • Reports of Evaluations

3. IACUC EVALUATIONS • At least Once Every Six Months • IACUC May Determine the Best Means…. • The Guide • USDA Regulations • PHS Assurance

4. IACUC EVALUATIONS • IACUC May Invite Ad Hoc Consultants to Assist • IACUC Remains Responsible • For the Evaluations • For the Reports

5. IACUC EVALUATIONS • OLAW’s Interpretation • IACUC Function / Responsibility • Committee Members Should Be Involved in the Process • No Member May be Involuntarily Excluded

6. IACUC EVALUATIONS - Program • Guide and CFR • Program Components to Consider • IACUC Membership and Functions • IACUC Records and Reporting Requirements • Husbandry & Veterinary Medical Care • Personnel Qualifications and Training • Occupational Health and Safety

7. IACUC EVALUATIONS – Facilities “George, can I pet the bunnies?” Lennie Of Mice and Men John Steinbeck

8. IACUC EVALUATIONS – Facilities • Animal Facility – Any and all buildings, rooms, areas, enclosures, or vehicles, including satellite facilities, used for animal confinement, transport, maintenance, breeding, or experiments inclusive of surgical manipulation.

9. IACUC EVALUATIONS – Facilities • Satellite Facility – any containment outside of a core facility or centrally designated or managed area in which animals are housed for more than 24 hours.

10. IACUC EVALUATIONS – Facilities • Animal Housing • Feed, Water, and Bedding • Cage Washing & Storage • Surgery and Surgical Support • Procedure Areas and Laboratories • Storage and Mechanical Areas

11. IACUC EVALUATIONS - Reports • Description of Adherence to the Guide and PHS Policy • Identify Departures and State the Reasons • Distinguish Significant v. Minor Deficiencies

12. IACUC EVALUATIONS - Reports • Reasonable and Specific Plan and Schedule • Identify AAALAC Accredited Facilities • Signatures of a Majority of the Members • Minority Views

13. IACUC EVALUATIONS - Reports • Upon Completion of Evaluations • Submit to Institutional Official • Maintained by Institution • Made Available to OLAW upon Request

14. IACUC EVALUATIONS • Use of AAALAC Site Visit for Evaluations • Report Must be Compliant with PHS Policy • Report must be Endorsed by IACUC as the Official Report and Must be Submitted to IO • Must be Compliant w/USDA Regs (if applicable) e.g., at least two (2) IACUC Members

15. IACUC EVALUATIONS • Areas of Concern • Lack of Required Contents, e.g. Checklist Only • Checklist Faux Pas • Limited Participation - Veterinarian &/or Chair • Missing Signatures / No Indication of Committee Input or Review

16. IACUC EVALUATIONS • Areas of Concern • No Indication of Submission to IO • Timeliness (Evaluations and/or Reports) • Reporting Channels • Years of “No Deficiencies”

17. IACUC EVALUATIONS • Areas of Concern • Significant (major) v. Not Significant (minor) • Program Review v. Facility Inspection • No Animals, No Inspection, No Documentation • Missed Areas

18. IACUC EVALUATIONS • Questions • OLAW Staff • http://grants.nih.gov/grants/olaw/olaw.htm

19. IACUC EVALUATIONS Thank You