Immunology & Serology. February 2006. The Immune System. The human immune system responds from attacks from outside the body. Consists of skin, t ears, saliva, mucous Thymus Spleen Lymph system Bone marrow White blood cells Antibodies Complement system Hormones. Antibodies.
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Antibodies, also called immunoglobulins
The antibodies inactivate antigens by
1. Recognition of antigens
2. Removal of antigen
1. The Abs make viruses/bacteria more susceptible to attack by macrophages.
2. Macrophages engulf the microbes by phagocytosis
White blood cell
There are a number of tests that diagnose disease based on the detection of antibodies. Some common techniques are listed below.
Method for identification of Ags in tissue sections & on cells, or for identifying Abs to them.
Disadvantages- subjective, time consuming, inconvenient for large scale screening.
1. Remove competing IgG that can cause false negative results.
2. Remove Rheumatoid Factor (RF) that can cause false positive results.