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toxicology - PowerPoint PPT Presentation


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The Science of Poisons. Beneficial Effects: Selective ToxicitySpecies selectivity / Economic Poisonseg, antibioticsCell-type Selectivity / Chemotherapyeg, radio-iodide for hyperthyroidUnwanted vs Wanted Effects: Drug DevelopmentAdverse EffectsDrug-related adverse effects (including Iatrogenic)Therapeutic ratioPathologic effects altering clearanceExposure to non-drug xenobioticsGI/ lungs/ skin.

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