Bugging the Bugs. Microbial Geneticist Bonnie Bassler: Investigating Bacterial Communications. Bonnie Bassler Is a Spy. Bassler, a bacterial geneticist at Princeton University, eavesdrops on bacteria. Question : What word describes bacteria that glow in the dark?.
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Microbial Geneticist Bonnie Bassler:
Investigating Bacterial Communications
Bassler, a bacterial geneticist at Princeton University, eavesdrops on bacteria.
What word describes bacteria that glow in the dark?
The bacteria Bassler investigates
Luminescent bacteria can make seafood glimmer blue-green.
Next time you see raw fish, turn out the lights and check out the glow!
Only glow when they are in a sufficiently large group (known as a quorum)
These changes culminate in an infection that can ambush and overwhelm our immune system defenses.
The bacteria appear relatively innocuous as they quietly grow in number.
What do we call such chemicals?
Give an example of a common biofilm.
V. harveyi communication systems
AI-2 contains the element boron
Autoinducer 2 may hold the key to disrupting quorum-sensing.
AI-2 and similar boron-containing molecules made in the laboratory could serve as decoys to subvert virulence and other quorum-sensing behaviors
In what ways might the knowledge that Bassler has gained about bacterial quorum-sensing be applied in human medicine?