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This study by JM Zheng and ZC Jia in Nature identifies the ATP-binding site and the allosteric AMP-binding site in the AceK enzyme. Insights into these sites can aid in understanding enzyme function and potential therapeutic applications. The research sheds light on the interaction between AceK and ATP/AMP, offering valuable information for further studies in biochemistry and drug development.
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The ATP-binding site and the allosteric AMP-binding site in AceK. JM Zheng & ZC Jia Nature000, 1-5 (2010) doi:10.1038/nature09088