Fundamentals of Biotechnology. Gene therapy. Gene therapy. The term gene therapy describes any procedure: intended to treat or alleviate disease by genetically modifying the cells of a patient.
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Gene augmentation therapy (GAT):
Target killing of the specific cells:
Direct cell killing:
Target inhibition of gene expression:
Targeted mutation correction:
Current gene therapy is exclusively somatic gene therapy, the introduction of genes into somatic cells of an affected individual.
The prospect of human germline gene therapy raises a number of ethical concerns, and is currently not sanctioned.