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NIH Training Grants, Fellowships, and Career Development Awards. Milton J. Hern á ndez, Ph.D. Director Office of Special Populations and Research Training National Institute of Allergy and Infectious Diseases (NIAID). Purpose of Ts, Fs, and Ks.

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NIH Training Grants, Fellowships, and Career Development Awards


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    1. NIHTraining Grants, Fellowships, and Career Development Awards Milton J. Hernández, Ph.D. Director Office of Special Populations and Research Training National Institute of Allergy and Infectious Diseases (NIAID)

    2. Purpose of Ts, Fs, and Ks • To ensure that we have an adequate number of highly trained scientists to meet our Nation’s present and future health research needs • Ultimately we want to see new generations of independent biomedical investigators

    3. Support by Career Stage- M.D. Track T35- NRSA Short Term Institutional Research Training Grant T32- NRSA Institutional Research Training Grant F32- NRSA Individual Postdoctoral Fellowship K01- Mentored Research Scientist Development Award K08- Mentored Clinical Scientist Research Career Development Award K23- Mentored Patient-Oriented Research Career Development Award K24- Mid-Career Investigator Award in Patient-Oriented Research K22- Different names for this transition award K99/R00- Pathway to Independence Award K01 K08 K23 K02- Independent Scientist Award F33- NRSA Senior Postdoctoral Fellowship K99/R00 Award Types T35 T32 F32 K22 K99 R00 K02 F33 K24 or High School Student Medical Student M.D. Clinical Training Phase Research Training Phase Faculty Position Independent Investigator Your Career Stage Diversity Supplements

    4. Support by Career Stage- Ph.D. Track Award Types K99/R00 T32 F31 T32 F32 K01 K22 K99 R00 K02 F33 or High School Student Graduate Student Ph.D. Faculty Position Independent Investigator Postdoc Phase Your Career Stage Diversity Supplements

    5. General Principles

    6. Training Grants (Ts) • NRSA- National Research Service Award • Legislated, program began in 1974 (P.L. 93-348) • Multi-slot awards • Domestic institutions only • Fund training programs for pre- and postdocs in any scientific area within our scientific mission • Can be basic or clinical • Trainees work in a mentor’s lab • MDs, PhDs, DVMs • Awards go the best training programs in the Nation

    7. Fellowships (Fs): • NRSA- National Research Service Award • Legislated, program began in 1974 (P.L. 93-348) • Individual awards under a mentor • Training can be at domestic or foreign institutions • Fund pre- and postdoc trainees in any scientific area within our scientific mission • Can be basic or clinical- most are basic • Most awardees are for Ph.D.s

    8. Career Development Awards (Ks) • Individual awards • Mostly for MDs • More senior award than a fellowship • Some mentored others not • Newer ones (K22 and K99/R00) are transition awards- for MDs and PhDs

    9. Mechanisms

    10. Training Grants • Some all predoc/some all postdoc • Most are a mixture of slots • Funds are mostly for tuition and trainees • Training Related Expenses may be used to defray costs such as staff salaries, equipment, research supplies, and other expenses directly related to the training program • Costs: • Tuition- 60% of requested tuition, capped at $16,000 ($21K for MD-PhD programs) • Stipends- $20,772 pre/ postdoc $36,996 (level 0)-$51,036 (level 7) • Training Related Expenses- $4,200 pre/$7,850 (post); both include health insurance • Travel- $400-$1000 • F&As- 8%

    11. F31s- Ruth Kirschstein NRSA Awards for Individual Predoc Fellowships to Promote Diversity in Health-related Research • Predoc fellowship for minorities and students with disabilities • Individual awards • Cannot change the scope, move fellowship, or change mentor without prior NIH approval • Tuition- 60% of requested tuition, capped at $16,000 ($21K for MD-PhD programs) • Stipends- $20,772 pre • Training Related Expenses- $4,200 includes health insurance • Travel- $400-$1000 • F&As- 8%

    12. F32sPostdoc Fellowships • Postdoc only • Individual award • Cannot change the scope, move fellowship, or change mentor without prior NIH approval • Stipends- $36,996 (level 0)-$51,036 (level 7) • Training Related Expenses- $7,850; includes health insurance • Travel- $400-$1000 • F&As- 8%

    13. F33sSenior Postdoc Fellowships • Not for postdocs who have been postdocs a long time • Used for associate or full professors who want to go off on a sabbatical • For MDs or PhDs • Few applicants- too little money • Stipend = $51,036 • Training Related Expenses- $7,850; includes health insurance • Travel- $400-$1,000

    14. K01Mentored Research Scientist Development Award • Used in different ways by ICs • MDs or PhDs • 3-5 years • Salary: $75,000/ yr + FBs • Research Support: $20,000/yr • F&As= 8%

    15. K02Independent Scientist Award • Best candidate is a “senior” assistant professor or “junior” associate professor • Close to or just got promoted and tenured • Must have independent grant support • Best award to have: R01 • MDs (very few) and PhDs • Salary support only • $75,000/yr + FBs for 5 years • Gives up salary support from all other NIH grants! • Relatively few applicants • F&As= 8%

    16. K08-Mentored Clinical Scientist Development AwardK23- Mentored Patient-Oriented Research Career Development Award • K08- for basic research project • K23- for clinical/ patient-oriented project • K08- 3 or 5 yr award • 3 yrs for more senior individual • 5 yrs for more junior individual, but must justify a “didactic” 2 yr phase • Salary: $75,000 + FBs/ yr • Research Support: • K08- $20,000/yr • K23- $25,000/yr • F&As= 8%

    17. K24Mid-Career Investigator Award in Patient-Oriented Research • Purpose: to provide support for clinician investigators to allow them protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for junior clinicians • 3-5 years • MDs • Salary- 25-50% at institutional rate (maximum Congressionally-mandated level) + FBs • Research Development Support- $50,000 • F&As= 8%

    18. K25Mentored Quantitative Research Development Award • For individuals from a quantitative background who want to apply their expertise to a biomedical problem • For engineering, mathematics, computer science- NOT individuals who are already working in a biomedical or epidemiological area • 3-5 years • Salary: $75,000 + FBs • Research Support: $20,000 • F&As= 8%

    19. K22 Research Scholar Development Award • Transition award for postdocs moving to positions of assistant professor • Two-phased application • Phase 1 • Scientific merit • No institution yet • If applicant gets a fundable score, they have a year to find a position as assistant professor • Phase 2 • Assistant Professor • Own lab • Significant start-up funds • Little teaching/ no administrative responsibilities • F&As= 8%

    20. K99/R00 Pathway to Independence Award • Transition award for postdocs moving to assistant professors positions • Has mentored phase • Citizenship and green card not required- new feature for any K • Has a mentored phase (K99) and an independent phase (R00) • VERY competitive

    21. Contact me: • mh35c@nih.gov • 301-496-3775