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How to Vaccine Asthmatic Chlidren - Dr. Sheetu Singh

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How to Vaccine Asthmatic Chlidren - Dr. Sheetu Singh

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  1. Effectiveness in asthmatic children Randomized, double-blind &placebo-controlled study was conducted in children with asthma 6-18 yrs of age, who had used medication for asthma in the previous year. They were recruited in general practices during the seasons 1999-2000 & 2000-2001. A total of 696 children were enrolled, of whom 347 were vaccinated with Influvac& 349 were in the placebo group • No serious adverse events were observed • Apart from daytime cough, no differences were found for the frequency or severity of asthma symptoms as an adverse reaction to vaccination • Found to have a moderately beneficial effect on quality of life in influenza-positive weeks of illness in children with asthma • No evidence that vaccination increased the risk of exacerbations of asthma

  2. Effectiveness in asthmatic children Reduce the risk of asthma exacerbation by 22% to 41%1 Study in children 0 to 12 years old with asthma, a beneficial clinical effect ( in no of lower RTI & acute otitis media) in vaccinated preschool children2 Ong et al reported a reduction in the use of oral steroids in vaccinated children with asthma3 Source: 1. Destefano F et al. Does influenza vaccination prevent asthma exacerbations in children?Kramarz P, J Pediatr. 2001 Mar; 138(3):306-10. 2. Smits AJet al. Clinical effectiveness of conventional influenza vaccination in asthmatic children. Epidemiol Infect. 2002;128(2):205–11. 3. Ong BA, Forester J, Fallot A. Does influenza vaccination improve pediatric asthma outcomes? J Asthma.2009;46(5):477–80

  3. Effectiveness in COPD pts Source: Poole PJ, et al. Influenza vaccine for patients with chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD002733.

  4. Sub unit VaccinevsSplit Vaccine • Source: 1. Beyer WE, Palache AM, Osterhaus AD. Comparison of Serology and Reactogenicity between Influenza Subunit Vaccines and Whole Virus or Split Vaccines: A Review and Meta-Analysis of the Literature. Clin Drug Investig. 1998;15(1):1-12. 2. PalacheAM. Influenza vaccines. A reappraisal of their use. Drugs. 1997 Dec;54(6):841-56.

  5. How to Vaccinate

  6. Vaccination Schedules * 2 doses at least 1 month apart for children receiving vaccine for the first time

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