1 / 10

Economic evaluation alongside clinical trials: The GALA trial

Economic evaluation alongside clinical trials: The GALA trial. Manuel Gomes, Marta Soares, Jo Dumville, David Torgerson Dep. of Health Sciences - University of York. Why is economic evaluation important?. The objective of the budget holder is to maximise health gains from a fixed budget

Download Presentation

Economic evaluation alongside clinical trials: The GALA trial

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Economic evaluation alongside clinical trials:The GALA trial Manuel Gomes, Marta Soares, Jo Dumville, David Torgerson Dep. of Health Sciences - University of York

  2. Why is economic evaluation important? Theobjectiveof the budget holder is to maximise health gains from a fixed budget There is an opportunity costassociated with each choice Economic evaluationaims to inform decisions about resource allocation - value for money

  3. What is economic evaluation? Comparative analysisof competing interventions with respect to: costs health benefits Characterisation of uncertaintysurrounding the decision Identify and make explicit the set ofcriteriaused for decision making

  4. Main methods for economic evaluation Cost-effectiveness analysis Health benefits measured in natural units: event-free days Cost-utility analysis Health benefits expressed as a single measure combining quality gains (morbidity) and quantity gains (longevity) Quality Adjusted Life Years (QALYs)

  5. Economic evaluation potential results + NE quadrant NW quadrant New intervention is - more costly - more beneficial New intervention is - more costly - less beneficial Differences in cost - + + 0 Differences in effectiveness New intervention is - less costly - less beneficial New intervention is - less costly - more beneficial SW quadrant SE quadrant -

  6. The GALA Trial Preliminary Economic Analysis Cost effectiveness analysis RCT based Perspective – health care provider Time horizon – 1 year Health outcome Event free survival (MI, stroke, death) Relevant resources

  7. The GALA TrialUnit Costs

  8. The GALA TrialResource Use

  9. The GALA TrialPreliminary Cost Estimation * LA minus GA ϮStandardt-tests

  10. The GALA TrialEllipse Curves

More Related