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COLLABORATORY RESEARCH PROJECTS: MACEWAN PHYSICAL SCIENCES Dr. Samuel Mugo

COLLABORATORY RESEARCH PROJECTS: MACEWAN PHYSICAL SCIENCES Dr. Samuel Mugo. Listen to Nature, Learn from Nature. “Being ‘less bad’ is no good.”. The world will not evolve past its current state of crisis by using the same thinking that created the situation. -Albert Einstein.

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COLLABORATORY RESEARCH PROJECTS: MACEWAN PHYSICAL SCIENCES Dr. Samuel Mugo

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  1. COLLABORATORY RESEARCH PROJECTS: MACEWAN PHYSICAL SCIENCESDr. Samuel Mugo

  2. Listen to Nature, Learn from Nature “Being ‘less bad’ is no good.” The world will not evolve past its current state of crisis by using the same thinking that created the situation. -Albert Einstein

  3. Collaboratory Research Project Themes • Novel Analytical Platforms for Environmental and Food monitoring Natural Products • Hormones and Antibiotics-NSERC project FATS and OILs Profiling Bioactive, sensory, antioxidants, allelopathic compounds Value added Green Products Destroy antibiotics in cattle manure: use it as fertilizer On-site integrated sampling techniques U of A: Dr Curtis Dr. Withey, Highmark Dr. Njenga, Dr Mellisa Hills ARDN

  4. FATS and OILs Transformations (natural catalysts) Green Products Oils and fats: Most important renewable materials. Exploit carboxylate chemistry Wax esters, Structured lipids, Biodiesel,

  5. Natural Products Profiling Bioactive, sensory, antioxidants, allelopathic compounds

  6. Natural Products: Antioxidants • If you keep food for a long time on shelf they go bad: Preserve • Natural antioxidants: • Synthetic antioxidants: TIME Quercetin-3-glucoside • No harmful physiological effects • Not Fat-soluble (mainly hydrophilic) • Economical Safety (Carcinogenic) Concerns?

  7. Antioxidants (polyphenolics) From Herbal Plants More effective than BHT and BHA Rosemary (Rosmarinus Officinalis L.): Common spice widely used in food processing Obtained by extraction with ethanol/methanol fraction Yanishlineva et al. Eur. J. Lipid. Technol. 108(2006): 776

  8. Antioxidants (polyphenolics) From Herbal Plants Oregano (Oreganum Vulgare L.) antimicrobial and antioxidant properties Yanishlineva et al. Eur. J. Lipid. Technol. 108(2006): 776

  9. Herbal Plants and Spices of Interest Botany Depart: JKUAT (KENYA) Plants from: Strychnos heningsii (muteta) Ixora scheffleri K.Schum Cure and Prophylaxis of arthritis • Compounds to look for with antioxidant activity: • flavonols, • flavonoids, • isoflavones, • diterpenes and • phenolic acids Clausena anisata (Give herbal preparations sweet smell) Tamarindus indica.

  10. Our research Often taken as a concoction for myriad remedies Figure 1. Myrianthus Hostii, an East African Herbal Plant Concomitant study of the secondary Metabolites • Seeds used to treat boils, bark decoction for lowering sugar level Used in the management of flu and cold; antimicrobial Piper capense Characterization of active compounds makes their use safer!

  11. Natural Products Aloe Vera allelopathic compounds Bioactive and sensory compounds

  12. Novel Analytical Platforms for Environmental and Food monitoring

  13. CHEMOMETRICs (DR. KAREN BURO • Using statistical tools to quickly interpret complex data quickly acquired by Fourier Transform Spectroscopic Methods: FTIR and RAMAN • Adulteration in Foods • Case of Melamine tainted Milk, cat food etc. • Nitrate tainted milk • Trans Fats in Cookies • Olive oil spiked with Canola oil

  14. NSERC-funded research on hormones and antibiotics Project: Development of a novel, practical approach for the detection, tracing and destruction of antibiotics and hormones in animal biowaste Collaborative project with Highmark Renewables Research, and part of the larger bioWaste to Energy for Canada Integration Initiative (BECii) Currently funded by a two-year $200,000 NSERCCCI grant Method development taking place entirely at the MacEwan campus, utilizingstart-of-art instrumentation and dedicated research space acquired as part of the new baccalaureate degree programs Project involves two MacEwan faculty members, one post-doctoral researchassociate, and employs four undergraduate students as research assistants eachyear.

  15. Equipment Infrastructure GC-MS LC Dual-laser Raman spectrometer (3 cm-1) with optical microscope LCQ Fleet ion trap MSn We service clients off-campus for a reasonable fee

  16. FT-IR Atomic absorption spectrometry 400 MHz NMR spectrometer iCAP (inductively coupled plasma spectroscopy) We service clients off-campus for a reasonable fee

  17. Challenges/opportunities Students Training Opportunity: Karl ayton, Alex Cerezo, Samuel Langman, Linh Tran, Jennifer, Lauren, Patrick, Merrill Singletonetc. We are collaboration crazy! It is the way to go Money- Getting access to money from other funding agencies (NSERC, ARDN, Canola growers Association, CIDA, CHIR, AACTI, AIF etc.

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