Hyponatremia in neonatology. Kirsten L Brunsvig 03.05.10. Sodium. Dominating cation in the ECF Princible determinant for extracellular osmolality Necessary for the maintenance of intravascular volume.
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Kirsten L Brunsvig
= syndrome of inappropriate ADH secretion
Rapid corrections may result in brain damage.
[Na] deficit x weight (kg) x 0.6
Total body water = 60-75% of weight
Usually use 60% to minimize the likelihood of overly rapid correction
[Na] deficit = [Na] desired – [Na] patient