CONCEPTS OF DISEASE CAUSATION. DR MIRZA INAMUL HAQ AP COMMUNITY MEDICINE. LEARNING OBJECTIVES. The student should learn disease process What are the theories of causation of disease? How is it transmitted? How it spreads? How it is distributed? And why?
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DR MIRZA INAMUL HAQ
AP COMMUNITY MEDICINE
The student should learn disease process
DISEASE CAN BE SIMPLY EXPLAINED
AS DISAT EASEOR ILL HEALTH
SOME DESCRIBE IT AS DISTURBANCE IN EQUILIBRIUM BETWEEN MAN AND HIS TOTAL ENVIRONMENT.
Henle and Koch have postulated that
STATED THAT AGENT, HOST AND ENVIRONMENTAL FACTORS WILL ACT AND INTERACT SYNERGISTICALLY AND ACT AS JOINT INDEPENDENT PARTNERS IN CAUSING THE DISEASE.
Agent (SEED) factors
DISEASE OCCURS ONLY WHEN THE HOST FACTORS AND ENVIRONMENTAL FACTORS MAKE THE AGENT SUFFICIENT ENOUGH TO CAUSE THE DISEASE
Host factors (SOIL)
A F G H J K
A R S T X
A B C D E
A L M N P Q
Causal constellations 1 2 3 4
A = NECESSARY CAUSE
B TO X = CAUSAL PARTNERS
LUNG CANCER IS CAUSED BY A CONSTELLATION OF CAUSES LIKE
THE DISEASE IS INITIATED AT THE CELLULAR LEVEL WHEN THE NECESSARY CAUSE (AGENT) BECOMES SUFFICIENT I.E. COMPLIMENTED BY ITS CAUSAL PARTNERS
Disease initiation at
Poor herd immunity
MODE OF TRANSMISSION THROUGH SOME VEHICLE OR VECTOR
TIME DISTRIBUTION OF THE DISEASE
INTERVENTIONS TAKEN TO PREVENT COMPLICATIONS
EITHER IN THE FORM OF