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The study shows enhanced tissue survival with diethylenetriamine NONOate (DETA-NO) treatment in flap surgery, as seen in the comparison of control flap vs. DETA-NO treated flap based on necrosis lines. This research by John A. Russell et al. was published in JRRD in 2010.
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Figure 1. Representative photograph of increased tissue survival noted following injection of nitric oxide donor DETA-NO. Arrows designate line of necrosis. (a) Control flap. (b) DETA-NO treated flap. DETA-NO = diethylenetriamine NONOate. John A. Russell, MS; et al. JRRD 2010; 47.1: 61-66