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Protecting Environmental Health in Schools – An Introduction to the Ethics and Toxicology. Keeping Students Safe. Steven G. Gilbert, PhD, DABT “A Small Dose of Toxicology” www.asmalldoseof.org. A Small Dose of Toxicology. See: www.asmalldoseof.org -- smdose. Small Dose of Toxicology.
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Protecting Environmental Health in Schools – An Introduction to the Ethics and Toxicology Keeping Students Safe Steven G. Gilbert, PhD, DABT “A Small Dose of Toxicology” www.asmalldoseof.org
A Small Dose of Toxicology See: www.asmalldoseof.org -- smdose
Vision for Child Health “Children can develop and mature in an environment that allows them to reach and maintain their full potential.”
Toxicology Definitions The study of poisons or the adverse effects of chemical and physical agents on living organisms.
Environmental Health “Conditions that ensure that all living things have the best opportunity to reach and maintain their full genetic potential.” Steven G. Gilbert, 1999
What Is This Pesticide? O CH3 CH3 N N 7 1 3 O N N CH3
Risk = Hazard X Exposure Key Words Dose / Response Individual Sensitivity
Paracelsus “All substances are poisons; there is none which is not a poison. The right dose differentiates a poison from a remedy.” Paracelsus (1493-1541)
An Individual View “The sensitivity of the individual differentiates a poison from a remedy. The fundamental principle of toxicology is the individual’s response to a dose.” S. G. Gilbert (1997)
Susceptibility of Children • Dose Response Issues • Higher metabolic rate • Different nutritional requirements • Rapidly dividing & migrating cells • Immature organs
Greek 2nd BC Lead History Lead Makes the Mind Give Way
Lead - Absorption Orally Consumed Lead Absorbed In Place of Calcium CHILDREN – 30-50% OF LEAD ADULTS – 5-10% OF LEAD Increased During Pregnancy
Half-life Of Lead • 25 DAYS -- BLOOD • 40 DAYS -- SOFT TISSUE • 20 YEARS -- BONE
Are we doing enough? CDC Lead level 10 to 2 Mcg/dL? Lead in the drinking water of Seattle schools! SB 5189 Reducing childhood lead exposure
WA State Hg Action Plan • Mercury Education and Reduction Act (MERA) – 2003 • Educate - schools, businesses, local governments, and the public about health effects, disposal, and reduction of use • January 1, 2006 - Primary and secondary schools can no longer purchase elemental mercury or mercury compounds, and must remove and properly dispose of bulk elemental mercury. http://www.doh.wa.gov/EHP/mercury/wadoing.htm
Insecticides (kill insects) Organochlorines Organophosphates Carbamates Synthetic Pyrethroids Herbicides (kill plants) Rodenticides (kill rodents) Fungicides (kill fungus) Fumigants (kill whatever) Classes Of Pesticides
Dietary exposure Pesticide residues on crops, dust –hand to mouth Community exposure Airborne drift from commercial app Contaminated drinking water Leaching from soils to ground water Other Exposure
Integrated Pest Management (IPM) • Focus – long-term prevention of pest problems • Reduce or eliminate chemical pest control methods • Monitor for the presence of pests before treating • Nonchemical strategies (make habitat less attractive, physical controls) • Learn about your pests
Precautionary Principle “When an activity raises threats of harm to human health or the environment, precautionary measures should be take even if some cause and effect relationships are not fully established scientifically.” Wingspread Conference, 1998.
Central components • Taking preventive action in the face of uncertainty • Shifting the burden of proof/responsibility to the proponents of an activity • Exploring a wide range of alternatives to possibly harmful actions • Increasing public participation in decision making • Wingspread Conference, 1998.
Knowledge - Responsibility • Children have a right to a safe, fair and healthy environment • Ethical Responsibility to share and use of knowledge • Duty to promote health and well being of children • Thoughtful public health advocate
Additional Information • A Small Dose of Toxicology • www.asmalldoseof.org For Additional Information contact Steven G. Gilbert, PhD, DABT E-mail: sgilbert@innd.org Web: www.asmalldoseof.org