Science for Global Health: Fostering International Research Collaboration

1. Science for Global Health: Fostering International Research Collaboration U.S. – Ukraine Joint Commission Meeting on Scientific and Technological Cooperation James Herrington, PhD, MPH Director Division of International Relations Fogarty International Center National Institutes of Health US Department of Health and Human Services January 18, 2011

2. Communicable, Maternal, Perinatal, and Nutritional Conditions Non-Communicable Diseases Injuries Global Burden of Disease, Reported Mortality by Cause, 2008 Pop. ~ 6 billion Pop. ~ 883 million Source: World Health Report, 2008; Disease Control Priorities Project, 2006

3. Global Burden of Disease, Reported Mortality by Cause: Non-Communicable Diseases, European Region, 2008 Source: World Health Report, 2008; Disease Control Priorities Project, 2006

4. Francis Collins, M.D. Director Elias Zerhouni, M.D. Director, NIH National Institute National Institute National Institute National Institute National Institute National Institute National Institute National Institute National Institute of Arthritis and National Cancer of Child Health National Institute of Arthritis and National Cancer of Child Health of Allergy and on Alcohol Abuse of Allergy and on Alcohol Abuse on Aging Musculoskeletal Institute and Human on Aging Musculoskeletal Institute and Human Infectious Diseases and Alcoholism Infectious Diseases and Alcoholism and Skin Diseases Development and Skin Diseases Development National Institute on National Institute National Institute National Institute on National Institute National Institute National Institute National Institute Deafness and Other of Dental and of Diabetes and National Institute National Eye Deafness and Other of Dental and of Diabetes and National Institute National Eye of Environmental of Environmental Communication Craniofacial Digestive and on Drug Abuse Institute Communication Craniofacial Digestive and on Drug Abuse Institute Health Sciences Health Sciences Disorders Research Kidney Diseases Disorders Research Kidney Diseases National Institute National Institute National Institute National Heart, National Human National Institute National Heart, National Human National Institute of Neurological National Institute National Institute of Neurological National Institute of General Lung, and Blood Genome Research of General Lung, and Blood Genome Research of Mental Health Disorders and of Nursing Research of Mental Health Disorders and of Nursing Research Medical Sciences Institute Institute Medical Sciences Institute Institute Stroke Stroke National Center National Center National Institute of National Center on National Center Fogarty National Institute of National Center on National Center Fogarty for Complementary National Library for Complementary National Library Biomedical Imaging Minority Health and for Research Biomedical Imaging International Minority Health and for Research International and Alternative of Medicine and Alternative of Medicine and Bioengineering Health Disparities Resources Center and Bioengineering Health Disparities Resources Center Medicine Medicine Center for Center for Center for Center for Clinical Center Information Clinical Center Information Scientific Review Scientific Review Technology Technology = Institutes and Centers that award grants

5. NIH Budget Total FY 2010 Budget: $31.3 billion 84% Outside NIH > 325,000 Scientists > 3,000 Organizations Worldwide 16% Inside NIH Intramural Research (10%) Staff & Buildings (4%) Other (2%)

6. Clinical Research Clinical Research Translational Research Translational Research Basic Research Basic Research Private Sector - $60 B NIH - $31 B Balanced National Biomedical Research Portfolio

7. NIH Offers Funding Programs to Support Scientists at Every Stage of their Career Approx. Stage of Research Training and Development Mechanism of Support Predoctoral Institutional Training Grant (T32) GRADUATE/ MEDICAL STUDENT Predoctoral Individual NRSA (F31) Predoctoral Individual MD/PhD NRSA (F30) Postdoctoral Institutional Training Grant (T32) Postdoctoral Individual NRSA (F32) POST DOCTORAL NIH Pathway to Independence (PI) Award (K99/R00) Mentored Research Scientist Development Award (K01) Mentored Clinical Scientist Development Award (K08) Mentored Patient-Oriented RCDA (K23) Mentored Quantitative RCDA (K25) EARLY Small Grant (R03) Research Project Grant (R01) Independent Scientist Award (K02) MIDDLE CAREER Midcareer Investigator Award in Patient-Oriented Research (K24) Exploratory/Development Grant (R21) SENIOR Senior Scientist Award (K05) *Graph represents a small sample of NIH funding mechanisms available.

8. John E. Fogarty International Center Mission • Address global health challenges through innovative and collaborative research and training programs • Support and advance the NIH mission through international partnerships • “Science for Global Health” • FY 2010 Appropriation $70 million

9. John E. Fogarty International Center Research and Research Training • ~$50 million in grant awards • 1/3 Research, 2/3 Research Training • Awards range $10,000 - $2 million • Low and Middle Income Countries • Research Capacity Development and Sustainability

10. John E. Fogarty International Center Extramural Training Grants – 14 Programs • Informatics Training for Global Health • Fogarty International Collaborative Traumaand Injury Research Training • International Research Ethics Education and Career Development • International Training Program inEnvironmental and Occupational Health • Global Research Training in Population Health (rolled into NCDs program) • International Collaborative Genetics Research Training (rolled into NCDs program) • Framework Programs for Global Health • Medical Education Partnerships Initiative (MEPI) • AIDS International Training and Research • Global Infectious Diseases Research Training • International Clinical, Operational, and Health Services Research Training Awards for HIV/AIDS and Tuberculosis • Fogarty International Clinical Scholars Research Training • Chronic, Non-Communicable Diseases and Disorders Across the Lifespan • International Clinical, Operational, and Health Services Research Training Awards for Malaria *Green = currently open for applications

11. John E. Fogarty International Center Extramural Research Grants – 8 Programs • Fogarty International Research Collaboration Award (FIRCA) • Brain Disorders in the Developing World • Ecology of Infectious Diseases (EID) • The Japan Society for the Promotion of Science (JSPS) • Int’l Tobacco and Health Research and Capacity Building Program • Global Research Initiative Program for New Foreign Investigators (GRIP) • Stigma and Global Health Research Program • International Cooperative Biodiversity Groups (ICBG) * Green = currently open for applications

12. NIH Collaboration with Ukraine – FY2010 • 5 of 24 (<10%) NIH Institutes and Centers awarded 16 grants totaling $1.9 million in peer-reviewed, foreign components of US awards to Ukrainian scientists and institutions • The awards were made by these Institutes/Centers (in rank order): • Fogarty International Center (FIC) • National Institute on Drug Abuse (NIDA) • National Heart, Lung, and Blood Institute (NHLBI) • National Cancer Institute (NCI) • National Eye Institute (NEI) • National Institute on Alcoholism and Alcohol Abuse (NIAAA)

13. NIH funded research in Ukraine – 2010 TOTAL$1,976,136 N=16 Awards

14. NIH Future Collaboration with Ukraine Career Transition Opportunity for Next Generation of Biomedical and Behavioral Research Scientists: • Visiting Program is open to scientists at all career levels • Two categories of program participants: • Visiting Fellows receive awards for research training • Visiting Scientists receive appointments to conduct research • Training opportunities at NIH available for foreign national scientists through the NIH Visiting Program http://dis.ors.od.nih.gov/visitingprogram/01_vpmain.html The NIH has long considered close interaction with foreign scientists in the conduct of collaborative research to be an essential ingredient in achieving its mission.

15. NIH Intramural Program, Visiting Fellows and Guest Researchers, by E.U. Member/Candidate Countries, 2009 N=1,084 x average stipend cost $50,000/yr = $54.2 million

16. NIH Transforming Medicine Through Discovery

17. For further information contact: MaryaLevintova, Ph.D. International Program Officer, Russia, Eurasia, and the Arctic Division of International Relations Email: Marya.Levintova@nih.gov Fogarty International Center National Institutes of Health 31 Center Drive, Building 31 Room B2C11 Bethesda, MD 20892-2220 Tel: 301-496-4784 Fax: 301-480-3414 Website: www.fic.nih.gov