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LUNG TRANSPLANTATION PowerPoint Presentation
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LUNG TRANSPLANTATION

LUNG TRANSPLANTATION

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LUNG TRANSPLANTATION

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  1. LUNG TRANSPLANTATION Pediatric Recipients ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  2. RECIPIENT AGE DISTRIBUTION FOR PEDIATRIC LUNG RECIPIENTS - NUMBER (Transplants: January 1986 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  3. RECIPIENT AGE DISTRIBUTION FOR PEDIATRIC LUNG RECIPIENTS - PERCENTAGE(Transplants: January 1986 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  4. DONOR TYPE DISTRIBUTION BY YEAR OF TRANSPLANT FOR PEDIATRIC LUNG RECIPIENTS (Transplants: 1986-2004) ISHLT NOTE: This figure includes only the lung transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of lung transplants worldwide has declined in recent years. 2006 J Heart Lung Transplant 2006;25:904-911

  5. DONOR TYPE DISTRIBUTION BY RECIPIENT AGE GROUP WITHIN ERA FOR PEDIATRIC LUNG RECIPIENTS (Transplants: January 1986 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  6. AGE DISTRIBUTION FOR DONORS OFPEDIATRIC LUNG RECIPIENTS(Transplants: January 1986 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  7. 89 84 86 AGE DISTRIBUTION OF PEDIATRIC LUNG RECIPIENTSBy Year of Transplant 75 69 69 67 67 65 62 55 49 48 43 Number of Transplants 20 6 4 4 1 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  8. NUMBER OF CENTERS REPORTING PEDIATRIC LUNG TRANSPLANTS ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  9. PEDIATRIC LUNG TRANSPLANTATION: Indications (Transplants: January 1991 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  10. DIAGNOSIS IN PEDIATRIC LUNG RECIPIENTSBY YEAR OF TRANSPLANTAge: 12-17 Years ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  11. PEDIATRIC LUNG RE-TRANSPLANTS Between January 1994 and June 2005 Time Between Previous and Current Transplant ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  12. PEDIATRIC LUNG RE-TRANSPLANTSBetween January 1994 and June 2004Stratified by Time Between Previous and Current Transplant ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  13. LUNG TRANSPLANTATIONKaplan-Meier Survival by Age Group (Transplants: January 1990 - June 2004) P = 0.72 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  14. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival by Procedure Type (Transplants: January 1990 - June 2004) P = 0.006 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  15. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival for Congenital Diagnosis(Transplants: January 1990 – June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  16. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival by Procedure TypeDiagnosis: Primary Pulmonary Hypertension (Transplants: January 1990 - June 2004) P = 0.0025 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  17. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival by Age Group (Transplants: January 1990 - June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  18. PEDIATRIC LUNG TRANSPLANTATIONConditional Kaplan-Meier Survival by Age Group(Transplants: January 1990 - June 2004) HALF-LIFE <1 Year: 8.8 Years 1-11 Years: n.c. 12-17 Years: 6.1 Years ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  19. PEDIATRIC LUNG TRANSPLANTATION Kaplan-Meier Survival by Era (Transplants: January 1988 - June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  20. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival by Donor Type for Recipients Age 11-17 Years(Transplants: January 1990 - June 2004) HALF-LIFE Deceased: 4.0 Years Living: 3.8 Years ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  21. PEDIATRIC LUNG RECIPIENTS Functional Status of Surviving Recipients(Follow-ups: April 1994-June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  22. PEDIATRIC LUNG RECIPIENTS Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  23. PEDIATRIC LUNG RECIPIENTS Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  24. PEDIATRIC LUNG RECIPIENTS Induction ImmunosuppressionFor transplants between January 2001 and June 2005 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  25. PEDIATRIC LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2001 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  26. PEDIATRIC LUNG TRANSPLANTATIONKaplan-Meier Survival Stratified by Induction Use(Transplants: January 2001 - June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  27. PEDIATRIC LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-up(Follow-ups: January 2001 and June 2005) NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  28. PEDIATRIC LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-up(Follow-ups: January 2001 and June 2005) 1 Year Follow-up (N = 154) 5 Year Follow-up (N = 83) NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  29. PEDIATRIC LUNG RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-up Report (Follow-ups: January 2001 and June 2005) NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  30. POST-LUNG TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  31. POST-LUNG TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  32. POST-LUNG TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Prevalence in Survivors within 7 Years Post-Transplant (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  33. Freedom from Bronchiolitis ObliteransFor Pediatric Lung Recipients(Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  34. FREEDOM FROM BRONCHIOLITIS OBLITERANSFor Pediatric Lung Recipients by Induction Use(Transplants: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  35. Freedom from Severe Renal Dysfunction*For Pediatric Lung Recipients(Follow-ups: April 1994 - June 2005) * Severe renal dysfunction = Creatinine > 2.5 mg/dl, dialysis or renal transplant ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  36. MALIGNANCY POST-LUNG TRANSPLANTATION FOR PEDIATRICSCumulative Incidence for Survivors(Follow-ups: April 1994 - June 2005) ”Other” includes Liver and primitive neuroectodermal tumor. ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  37. Freedom from MalignancyFor Pediatric Lung Recipients(Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  38. PEDIATRIC LUNG TRANSPLANT RECIPIENTS: Cause Of Death(Deaths: January 1992- June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911