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LUNG TRANSPLANTATION

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  1. LUNG TRANSPLANTATION Overall ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  2. NUMBER OF LUNG TRANSPLANTS REPORTED BY YEAR AND PROCEDURE TYPE NOTE: This figure includes only the lung transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as representing changes in the number of lung transplants performed worldwide. ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  3. AVERAGE CENTER VOLUMELung Transplants: January 1, 2000 - June 30, 2011 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  4. LUNG TRANSPLANTS Transplant Recipient Age by Year of Transplant(Transplants: January 1, 1987 – June 30, 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  5. AGE DISTRIBUTION OF LUNG TRANSPLANT RECIPIENTS (1/1985-6/2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  6. AGE DISTRIBUTION OF LUNG TRANSPLANT RECIPIENTS BY ERA ISHLT Transplants with unknown recipient age were excluded from this tabulation. 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  7. LUNG TRANSPLANTS Donor Age by Year of Transplant(Transplants: January 1, 1987 – June 30, 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  8. DONOR AGE DISTRIBUTION FOR LUNG TRANSPLANTS (1/1985-6/2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  9. DONOR AGE DISTRIBUTION FOR LUNG TRANSPLANTS BY ERA ISHLT Transplants with unknown donor age were excluded from this tabulation. 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  10. LUNG TRANSPLANTATION Adult Recipients ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  11. AGE DISTRIBUTION OF ADULT LUNG TRANSPLANT RECIPIENTS (1/1985-6/2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  12. AGE DISTRIBUTION OF ADULT LUNG TRANSPLANT RECIPIENTS BY ERA ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  13. AGE DISTRIBUTION OF ADULT LUNG TRANSPLANT RECIPIENTS BY ERA Median age by era 1985-1994 = 47 years 1995-2003 = 51 years 2004-6/2011 = 55 years ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  14. ADULT LUNG TRANSPLANTSKaplan-Meier Survival(Transplants: January 1994 - June 2010) p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  15. ADULT LUNG TRANSPLANTSIndications(Transplants: January 1995 - June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  16. ADULT LUNG TRANSPLANTSDistribution of Procedure Type for Major Indications by Year ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  17. ADULT LUNG TRANSPLANTS Procedure Type within Indication, by Year ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  18. ADULT LUNG TRANSPLANTS Indications for Single Lung Transplants (Transplants: January 1995 - June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  19. ADULT LUNG TRANSPLANTS Indications for Bilateral/Double Lung Transplants (Transplants: January 1995 - June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  20. ADULT LUNG TRANSPLANTSMajor Indications By Year (%) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  21. ADULT LUNG TRANSPLANTSMajor Indications By Year (Number) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  22. ADULT LUNG TRANSPLANTSAge Distribution By Location (Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  23. ADULT LUNG TRANSPLANTSDiagnosis Distribution By Location(Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  24. ADULT LUNG TRANSPLANTSDiagnosis Distribution By Location and Era(Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  25. ADULT LUNG TRANSPLANTSDonorAge Distribution By Location(Transplants: January 2000 – June 2011) ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  26. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Era (Transplants: January 1988 - June 2010) 1988-95 vs. 1996-2003: p < 0.0001 1988-95 vs. 2004-6/2010: p <0.0001 1996-2003 vs. 2004-6/2010: p <0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  27. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Age Group (Transplants: January 1990 - June 2010) All pair-wise comparisons are significant at p < 0.05 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  28. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Gender(Transplants: January 1990 - June 2010) p < 0.0001 N at risk = 119 N at risk = 102 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  29. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Diagnosis(Transplants: January 1990 - June 2010) All comparisons with Alpha-1 and CF are statistically significant at < 0.05 COPD vs. IPF: p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  30. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Diagnosis Conditional on Survival to 3 Months (Transplants: January 1990 - June 2010) All comparisons are statistically significant at 0.05 except Alpha-1 vs. COPD and CF vs. IPAH ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  31. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Diagnosis Conditional on Survival to 1 Year (Transplants: January 1990 - June 2010) All comparisons are statistically significant at 0.05 except Alpha-1 vs. Sarcoidosis, CF vs. IPAH and COPD vs. IPF ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  32. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type(Transplants: January 1990 - June 2010) Diagnosis: Alpha-1 Antitrypsin Deficiency p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  33. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type(Transplants: January 1990 - June 2010) Diagnosis: Alpha-1 Antitrypsin Deficiency p = 0.0008 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  34. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type(Transplants: January 1990 - June 2010) Diagnosis: Emphysema/COPD p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  35. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type(Transplants: January 1990 - June 2010) Diagnosis: Emphysema/COPD p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  36. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type(Transplants: January 1990 - June 2010) Diagnosis: Idiopathic Pulmonary Fibrosis p < 0.0001 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  37. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type(Transplants: January 1990 - June 2010) Diagnosis: Idiopathic Arterial Pulmonary Hypertension p = 0.0003 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  38. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type and Era(Transplants: January 1990 - June 2010) Diagnosis: Emphysema/COPD, Single Lung 1990-1997 vs. 1998-2004: p < 0.0001 1990-1997 vs. 2005-6/2010: p < 0.0001 1998-2004 vs. 2005-6/2010: p = 0.8250 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  39. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type and Era(Transplants: January 1990 - June 2010) Diagnosis: Emphysema/COPD, Double Lung 1990-1997 vs. 1998-2004: p = 0.0041 1990-1997 vs. 2005-6/2010: p = 0.0106 1998-2004 vs. 2005-6/2010: p = 0.6989 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  40. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type and Era(Transplants: January 1990 - June 2010) Diagnosis: Cystic Fibrosis, Double Lung 1990-1997 vs. 1998-2004: p < 0.0001 1990-1997 vs. 2005-6/2010: p < 0.0001 1998-2004 vs. 2005-6/2010: p = 0.1703 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  41. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type and Era(Transplants: January 1990 - June 2010) Diagnosis: Idiopathic Pulmonary Fibrosis, Single Lung 1990-1997 vs. 1998-2004: p = 0.0101 1990-1997 vs. 2005-6/2010: p = 0.0003 1998-2004 vs. 2005-6/2010: p = 0.1816 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  42. ADULT LUNG TRANSPLANTS Kaplan-Meier Survival By Procedure Type and Era(Transplants: January 1990 - June 2010) Diagnosis: Idiopathic Pulmonary Fibrosis, Double Lung 1990-1997 vs. 1998-2004: p = 0.0006 1990-1997 vs. 2005-6/2010: p < 0.0001 1998-2004 vs. 2005-6/2010: p = 0.0082 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  43. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Donor CMV status/Recipient CMV status(Transplants: October 1999 – June 2010) D(-)/R(-) vs. D(+)/R(-): p < 0.0001 D(-)/R(-) vs. D(+)/R(+): p < 0.0001 D(-)/R(+) vs. D(+)/R(-): p < 0.0001 D(-)/R(+) vs. D(+)/R(+): p = 0.0006 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  44. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Era(Transplants: October 1999 – June 2010)Donor CMV status/Recipient CMV status = D(-)/R(-) p = 0.4120 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  45. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Era(Transplants: October 1999 – June 2010)Donor CMV status/Recipient CMV status = D(-)/R(+) p = 0.7314 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  46. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Era(Transplants: October 1999 – June 2010)Donor CMV status/Recipient CMV status = D(+)/R(-) p = 0.1570 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  47. ADULT LUNG TRANSPLANTSKaplan-Meier Survival by Era(Transplants: October 1999 – June 2010)Donor CMV status/Recipient CMV status = D(+)/R(+) p = 0.9050 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  48. PERCENTAGE OF ADULT LUNG TRANSPLANT RECIPIENTS Experiencing Rejection between Transplant Discharge and 1-Year Follow-Up Stratified by Donor/Recipient CMV Status (Follow-ups: July 2004 - June 2011) Analysis is limited to patients who were alive at the time of the follow-up No comparisons were statistically significant at 0.05 D(-)/R(-): N = 1,362 D(-)/R(+): N = 1,672 D(+)/R(-): N = 1,859 D(+)/R(+): N = 2,979 ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  49. PERCENTAGE OF ADULT LUNG TRANSPLANT RECIPIENTS Experiencing Rejection between Transplant Discharge and 1-Year Follow-Up Stratified Donor/Recipient CMV Status (Follow-ups: July 2004 - June 2011) Treated rejection = Recipient was reported to (1) have at least one acute rejection episode that was treated with an anti-rejection agent; or (2) have been hospitalized for rejection. No rejection = Recipient had (i) no acute rejection episodes and (ii) was reported either as not hospitalized for rejection or did not receive anti-rejection agents. ISHLT Analysis is limited to patients who were alive at the time of the follow-up 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095

  50. ADULT LUNG TRANSPLANTS (1/1998-6/2010)Risk Factors For 1 Year Mortality N = 14,762 Reference group = COPD/Emphysema, Single lung *Other = All diagnoses other than COPD, IPAH, IPF, cystic fibrosis, pulmonary fibrosis,bronchiectasis,alpha-1 antitrypsin deficiency, retransplant and LAM. ISHLT 2012 J Heart Lung Transplant.  2012 Oct; 31(10): 1045-1095