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Prefrontal Cortex transcranial Direct Current Stimulation via a Combined High Definition and Conventional Electrode Montage: A FEM modeling study. Dennis Q. Truong, Abhishek Datta , Jiansong Xu , Felipe Fregni , and Marom Bikson Neural Engineering Laboratory

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slide1

Prefrontal Cortex transcranial Direct Current Stimulation via a Combined High Definition and Conventional Electrode Montage: A FEM modeling study

Dennis Q. Truong, AbhishekDatta, JiansongXu, Felipe Fregni, and MaromBikson

Neural Engineering Laboratory

Department of Biomedical Engineering,

City College of the City University of New York, NY

*Research supported by The Wallace Coulter Foundation

tdcs basics
tDCS Basics
  • Typicallysubthreshold brain stimulation
    • Action potentials are not directly caused, rather excitability is enhanced or suppressed
  • Enhanced or Suppressed cortical excitability is due to polarity.
heuristic montages
Heuristic Montages
  • Traditionally montages have been created by “rule of thumb”
    • Active Pad over a target region.
heuristic montages1
Heuristic Montages
  • Traditionally montages have been created by “rule of thumb”
    • Active Pad over a target region.

M1

heuristic montages2
Heuristic Montages
  • Traditionally montages have been created by “rule of thumb”
    • Active Pad over a target region.

Broca’s

heuristic montages3
Heuristic Montages
  • Traditionally montages have been created by “rule of thumb”
    • Active Pad over a target region.

Wernicke’s

heuristic montages4
Heuristic Montages
  • Traditionally montages have been created by “rule of thumb”
    • Active Pad over a target region.

Dorsal Lateral Prefronal Cortex

(F8)

heuristic montages5
Heuristic Montages
  • Traditionally montages have been created by “rule of thumb”
    • Active Pad over a target region.
    • Return Pad is simply elsewhere.

F8 - SO

tdcs is polarity sensitive
tDCS is Polarity Sensitive
  • Both the “Active” and “Return” stimulate (enhanced or suppressed excitability)
an alternative to contralateral supraorbital
An Alternative to ContralateralSupraorbital
  • Both the “Active” and “Return” stimulate (enhanced or suppressed excitability)

“2x1” Hybrid

heuristic design is limited
Heuristic Design is Limited
  • The location of the return pad effects current distribution.
slide13

Stimulation “over” is not Stimulation “of”

  • Peak Electric field may or may not be on be directly under the active electrodes
slide14

Stimulation “over” is not Stimulation “of”

  • Peak Electric field may or may not be on be directly under the active electrodes
summary
Summary
  • Montage design does not obey a simple rule of thumb.
    • Active Electrodes do not necessarily cause peak field at the target.
    • Return Electrodes need to be carefully considered.
  • Big Picture: Clinicians could use better guidelines for montage designs. i.e. – database of montage models