Phylogeography. John Brookfield Ecology Club 11 th February 2010. Circular DNAs derived from bacterial symbionts 16kb, 37 genes (in humans) Rapid evolutionary rates in warm blooded vertebrates (particularly in “D loop”) Maternally transmitted and non-recombining. Mitochondrial DNAs.
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11th February 2010
16kb, 37 genes (in humans)
Rapid evolutionary rates in warm blooded vertebrates (particularly in “D loop”)
Maternally transmitted and non-recombiningMitochondrial DNAs
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Sou Nor Sou Nor Sou Nor Sou Nor
Nor Nor Nor Nor Nor Sou Sou Sou Sou Sou
Inbreeding (specified by F ), when homozygotes exceed p2 +q2
FST = (0.8-0.2)2/(4x0.5x0.5)=0.36
How many heterozygotes expected (Hardy-Weinberg)=2p(1-p)=0.50
How many seen=
FST = (0.9-0.1)2/(4x0.5x0.5)=0.64
FST = (1.0-0.0)2/(4x0.5x0.5)=1.00
FST = (0.6-0.4)2/(4x0.5x0.5)=0.04
Linkage Disequilibrium: Association of A and B and association of a and b
Samples individuals and genotypes at many loci migration and mixing)
Creates subpopulations where there are Hardy-Weinberg proportions and linkage equilibrium within subpopulations
Assigns individuals to subpopulations
http://pritch.bsd.uchicago.edu/structure.htmlMethods: STRUCTURE- Jonathan Pritchard
G. Guillot, Estoup, A., Mortier, F. Cosson, J.F migration and mixing). A spatial statistical model for landscape genetics. Genetics, 170, 1261-1280, 2005.
Selective Sweeps migration and mixing)
Complete or partial