Carbohydrate Utilization During Exercise. Are CHO important during exercise?. 1.) Fatigue often associated with CHO depletion. 2.) CHO, OAA Fat metabolism can only support exercise at 50% VO 2 max. 3.) Hypoglycemia associated with liver CHO depletion.
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2.) CHO, OAA Fat metabolism can only support exercise at 50% VO2 max.
3.) Hypoglycemia associated with liver CHO depletion.
Recruitment order of slow twitch vs. Fast twitch fibers
-Energy state of muscle cell with impact from substrate supply
cytosolic Ca++ - activates phosphorylase kinase
ADP, AMP, Pi - allosteric activators of phosphorylase
-Need for Pi as a substrate for phosphorylase
-Glycogen - allosteric activator of phosphorylase
-Plasma FFA FFA glycogen use
FFA glycogen use
-FFA citrate - PFK-1
PDH Kinase P-PDH
-Caffeine glycogen use
Corn Oil/Heparin glycogen use
-Plasma Glucose - Hypoglycemia glycogen use
Epi/N-Epi via receptors C-AMP
- blockade glycogen use
Removal of adrenal medulla glycogen use