Fungal infections. Lobna AL Juffali,Msc. Introduction. Primary or “pathogenic” fungi that can cause disease in both healthy and immunocompromised individuals Histoplasmosis Coccidioidomycosis cryptococcosis Blastomycosis , paracoccidioidomycosis , sporotrichosis ,. Introduction.
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Lobna AL Juffali,Msc
Primary or “pathogenic” fungi that can cause disease in both healthy and immunocompromised individuals
Fungi found only in immunocompromised host such as
with progressive disease or with extrapulmonary disease should be treated with antifungals.
(1) the acute onset of fever, tachycardia, tachypnea, and occasionally chills or hypotension (similar to bacterial sepsis);
(2) intermittent fevers;
(3) progressive deterioration with or without fever;
(4) hepatospleniccandidiasis manifested only as fever while the patient is neutropenic.
Superficial or locally invasive infections of the ear, skin, or appendages can often be managed with topical antifungal therapy.
(2) an eschar over the nose, sinuses, or palate;
(3) the presence of characteristic radiographic findings, including wedge-shaped infarcts, nodular densities, or new cavitary lesions; or
(4) any clinical manifestation suggestive of orbital or cavernous sinus disease or an acute vascular event associated with fever.