Cardiac Tissue Matrix. Katelyn Pate. Statistics. Heart disease and stroke are the 1 st and 3 rd leading cause of death in the U.S. They account for 40% of all deaths, more than all cancer combined Congenital heart defects occur in nearly 14 of every 1000 newborn children
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Heart disease and stroke are the 1st and 3rd leading cause of death in the U.S.
They account for 40% of all deaths, more than all cancer combined
Congenital heart defects occur in nearly 14 of every 1000 newborn children
Most common congenital defect and leading cause of death in first year of life
Low engraftment and cell survival
Improved cell retention over injection via a syringe
Offers customization using growth factors
Still low engraftment and cell survival
Deliver cells with immediate function and capacity for vascular and electromechanical integration with the heart
Difficult to create a scaffold that displays functional and morphological properties of native heart muscles