Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules)

1. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR (Generic Venlafaxine Hydrochloride Capsules) is used to treat patients suffering from depression as well as prevent a relapse of depression. Venlor XR (Venlafaxine Hydrochloride extended-release capsules) is indicated for the treatment of major depressive disorder, Generalized Anxiety Disorder (GAD), Social Anxiety Disorder, also known as Social Phobia as well as for the treatment of panic disorder. It is also used for the prevention of relapses of the initial episode of depression or for the prevention of the recurrence of new depressive episodes. Depression interferes with daily life for weeks or longer and causes pain for both the patient and those who care about the person suffering from it. Depression is a relatively common but serious illness which can get better with treatment. Medications, psychotherapies, and other methods can effectively treat people suffering from depression. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Active Ingredient The active ingredient present in Venlor XR capsules is Venlafaxine Hydrochloride. Each extended-release capsule contains Venlafaxine hydrochloride equivalent to 37.5 mg, 75 mg, or 150 mg of Venlafaxine respectively. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Chemical Structure The structure of Venlafaxine Hydrochloride is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR capsules are manufactured by Cipla Limited, India in the strengths of 37.5 mg, 75 mg and 150 mg. (Website: https://www.cipla.com/ https://www.cipla.com/ ) URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlafaxine Hydrochloride Capsules – Brand Names Venlafaxine Hydrochloride Capsules are available under various brand names such as Effexor, Effexor XR, Lanvexin, Viepax, Venlor, Venlor-XR, Venla, Veniz-XR, Ven-OD, Venlift and Trevilor . © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Uses of Venlor XR Capsules Venlor XR (Generic Venlafaxine Hydrochloride Capsules) is used to treat depression. It is also used to treat general anxiety disorder, social anxiety disorder, and panic disorder. Venlafaxine belongs to a group of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRI). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR Capsules - Dosage The dosage of Venlor XR Capsules Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) is given below: Venlor XR should be administered in a single dose with food either in the morning or in the evening at approximately the same time every day. Each capsule has to be swallowed whole with fluid and not divided, crushed, chewed, or placed in water. The dosage of Venlor XR varies as per the indication being treated. The recommended dosage of Generic Venlafaxine Hydrochloride capsules for various indications is given below: Major Depressive Disorder: Major Depressive Disorder: For most patients, the recommended starting dose for Generic Effexor XR is 75 mg/day, administered in a single dose. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR Capsules - Dosage The dosage of Venlor XR Capsules Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) is given below: Generalized Anxiety Disorder: Generalized Anxiety Disorder: For most patients, the recommended starting dose for Generic Effexor XR is 75 mg/day, administered in a single dose. Social Anxiety Disorder (Social Phobia): Social Anxiety Disorder (Social Phobia): The recommended dose of Generic Effexor XR (Venlafaxine Hydrochloride) is 75 mg/day, administered in a single dose. Panic Disorder: Panic Disorder: The recommended initial dose of Generic Effexor XR is a single dose of 37.5 mg/day for 7 days. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Contraindications Venlor XR Capsules are contraindicated in patients with a hypersensitivity to Venlafaxine Hydrochloride or to any excipients in the formulation. Concomitant use of Generic Venlafaxine in patients taking monoamine oxidase inhibitors (MAOIs) is also contraindicated. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Storage Instructions Venlor XR capsules (Generic Venlafaxine Hydrochloride capsules) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Warnings Clinical Worsening/Suicide Risk: Monitor for clinical worsening and suicide risk. Serotonin Syndrome: Risk increases with concomitant use of other serotonergic drugs. Discontinue Effexor XR and initiate supportive treatment if serotonin syndrome occurs. Elevations in Blood Pressure: Control hypertension before initiating treatment. Monitor blood pressure regularly during treatment. Abnormal Bleeding: Venlor XR may increase risk of bleeding events. Caution patients about the risk of bleeding associated with the concomitant use of Venlafaxine XR and NSAIDs, aspirin, or other drugs that affect coagulation. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Warnings Angle Closure Glaucoma: Angle closure glaucoma has occurred in patients with untreated anatomically narrow angles treated with antidepressants. Activation of Mania/Hypomania: Use cautiously in patients with bipolar disorder. Caution patients about the risk of activation of mania/hypomania. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR Capsules Side Effects The side effects most commonly associated with Venlor XR (Generic Venlafaxine XR Capsules) administration are nervous system complaints, such as headache, dizziness, insomnia, somnolence, nervousness and dry mouth; gastrointestinal complaints, including anorexia, nausea and constipation; and abnormal ejaculation/orgasm, sweating and asthenia. Many of the frequently observed side effects are dose related. With continued treatment, these adverse effects generally decrease in frequency and intensity, and usually do not require discontinuation. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR Capsules Overdose Electrocardiogram changes (e.g. prolongation of the QT interval, bundle-branch block, and QRS prolongation), sinus and ventricular tachycardia, bradycardia and seizures, hypotension, vertigo, serotonin syndrome and changes in the level of consciousness have been reported in association with an overdose of Venlafaxine capsules (Venlor XR capsules), usually when in combination with alcohol and/or other CNS drugs. Published retrospective studies report that Venlafaxine (Venlor XR capsules) overdosage may be associated with an increased risk of fatal outcomes compared to that observed with SSRI antidepressant products, but lower than that for tricyclic antidepressants. Epidemiological studies have shown that Venlafaxine-treated patients have a higher pre-existing burden of suicide risk factors than SSRI-treated patients. The extent to which the finding of an increased risk of fatal outcomes can be attributed to the toxicity of venlafaxine in overdosage as opposed to some characteristic(s) of Venlafaxine-treated patients is not clear. Prescriptions for Venlafaxine should be written for the smallest quantity of capsules consistent with good patient management, in order to reduce the risk of overdose. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR Capsules Overdose Treatment should consist of those general measures employed in the management of overdosage with any antidepressant including Venlor XR. Ensure an adequate airway, oxygenation, and ventilation. Monitor cardiac rhythm and vital signs. General supportive and symptomatic measures are also recommended. Induction of emesis is not recommended. Gastric lavage with a large bore orogastric tube with appropriate airway protection, if needed, may be indicated if performed soon after ingestion or in symptomatic patients. Activated charcoal should be administered. Due to the large volume of distribution of this drug, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit. No specific antidotes for Venlafaxine Hydrochloride (Venlor XR Capsules) are known. No specific antidotes for Venlafaxine Hydrochloride (Venlor XR Capsules) are known. In managing overdosage, consider the possibility of multiple drug involvement. The physician should consider contacting a poison control center for additional information on the treatment of any overdose. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) Venlor XR Capsules During Pregnancy Venlafaxine Hydrochloride (Venlor XR Capsules) has been classified by the US FDA as Pregnancy Category C. Patients should be advised to notify their doctor if they become pregnant or intend to become pregnant during treatment with Generic Venlafaxine Hydrochloride XR Capsules (Venlor XR). Venlafaxine did not cause malformations in offspring of rats or rabbits given doses up to 2.5 times (rat) or 4 times (rabbit) the maximum recommended human daily dose on a mg/m2 basis. Since animal reproduction studies are not always predictive of human response and there have been no controlled studies conducted in pregnant women, Venlor XR Capsules should be used during pregnancy only if clearly needed. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Venlor XR Capsules (Generic Venlafaxine Hydrochloride Capsules) For more details on Venlor XR Capsules click here Venlor XR (Generic Venlafaxine Hydrochloride Capsules) by Cipla Limited, India. URL: URL: https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html https://www.clearskypharmacy.biz/generic-effexor-xr-venlor-xr-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )