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Quality Assessment for Routine Clinical MR Spectroscopy. Diana M. Lindquist, PhD Assistant Professor of Radiology. Purpose. Clinical indication: apparently abnormal metabolite ratios in infant with normal imaging findings.

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quality assessment for routine clinical mr spectroscopy

Quality Assessment for Routine Clinical MR Spectroscopy

Diana M. Lindquist, PhD

Assistant Professor of Radiology

purpose
Purpose
  • Clinical indication: apparently abnormal metabolite ratios in infant with normal imaging findings.
  • Quality control is as important in clinical spectroscopy as in research
  • Develop a simple short protocol for quality control in clinical MRS
    • Localization
    • Spectral data
methods
Methods
  • Standard head coil and manufacturer’s phantom
  • Protocol
    • Axial localizer
    • 3 voxels (8 cm3)
    • PRESS
  • Total time: 30 minutes
results voxel localization
Results: Voxel Localization
  • Mean voxel size was 20.2 (± 0.8) by 18.9 (± 0.4) mm2 in-plane
  • One voxel is adequate; scan time reduced from 30 to 15 minutes
sample spectra
Sample spectra

NAA

Cr

Cho

Lac

TE 35 ms

TE 144 ms

conclusions
Conclusions
  • Following implementation of this protocol, we are now able to detect and correct scanner instabilities.
  • QC data are useful as a monitor of system performance
  • Scheduling still difficult even with a 15 minute exam.