1 / 128

HEART TRANSPLANTATION

ISHLT. 2010. J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141. HEART TRANSPLANTATION. Pediatric Recipients. ISHLT. 2010. J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS (Transplants: January 1996 - June 2009). ISHLT. 2010.

charlesd
Download Presentation

HEART TRANSPLANTATION

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 HEART TRANSPLANTATION Pediatric Recipients

  2. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2009)

  3. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2009)

  4. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTSBy Year of Transplant NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of hearts transplanted worldwide has increased and/or decreased in recent years.

  5. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS

  6. NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  7. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 AVERAGE CENTER VOLUME AND PERCENTAGE OF TRANSPLANTS BY CENTER VOLUMEPediatric Heart Transplants: January 1, 1997 - June 30, 2009

  8. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 DISTRIBUTION OF TRANSPLANTS BY CENTER VOLUMEPediatric Heart Transplants: January 1, 1997 - June 30, 2009

  9. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART RE-TRANSPLANTSBy Transplant YearRe-transplants: January 1994 – December 2008 Only patients who were less than 18 years old at the time of re-transplant are included.

  10. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART RE-TRANSPLANTSBy Inter-transplant IntervalRe-transplants: January 1994 - June 2009 Only patients who were less than 18 years old at the time of re-transplant are included. Analysis is based on the age at the time of re-transplant

  11. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 KAPLAN-MEIER SURVIVAL RATES FOR PEDIATRIC HEART RETRANSPLANTS STRATIFIED BY INTER-TRANSPLANT INTERVALRe-transplants: January 1994 - June 2008 Only patients who were less than 18 years old at the time of re-transplant are included.

  12. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: < 1 Year)

  13. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 1-10 Years) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  14. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 11-17 Years) ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  15. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival (Transplants: 1/1982-6/2008)

  16. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival (Transplants: 1/1982-6/2008)

  17. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival for Recent Era (Transplants: 1/1999-6/2008)

  18. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era(Transplants: 1/1982-6/2008)

  19. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTATION Kaplan-Meier Survival by Era (Transplants: 1/1982-6/2008)Age: < 1 Year

  20. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (Transplants: 1/1982-6/2008)Age: 1-10 Years

  21. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (Transplants: 1/1982-6/2008)Age: 11-17 Years

  22. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS:AVERAGE CENTER VOLUME DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2009

  23. PEDIATRIC HEART TRANSPLANTATION Kaplan-Meier Patient vs. Graft Survival (Transplants: 1/1999-6/2008)Average Center Volume: 1-4 Transplants per Year ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  24. PEDIATRIC HEART TRANSPLANTATION Kaplan-Meier Patient vs. Graft Survival (Transplants: 1/1999-6/2008)Average Center Volume: 5-9 Transplants per Year ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  25. PEDIATRIC HEART TRANSPLANTATION Kaplan-Meier Patient vs. Graft Survival (Transplants: 1/1999-6/2008)Average Center Volume: 10-19 Transplants per Year ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  26. PEDIATRIC HEART TRANSPLANTS:AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2009 ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141

  27. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS:DIAGNOSIS DISTRIBUTION BY LOCATION Transplants between January 2000 and June 2009

  28. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS:DONOR AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2009

  29. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors For 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=3,838 Reference diagnosis = cardiomyopathy

  30. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Borderline Significant Risk Factors For 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=3,838

  31. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS(1/1996-6/2008)Risk Factors for 1 Year Mortality N=3,838

  32. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year MortalityRecipient Age NOTE: The impact of age should be considered in the context of height and diagnosis+age. N=3,838

  33. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year MortalityRecipient Height NOTE: The impact of height should be considered in the context of age and diagnosis+age. N=3,838

  34. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year MortalityDonor Age ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=3,838

  35. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year MortalityPre-TransplantCreatinine N=3,838

  36. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year MortalityIschemia Time ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=3,838

  37. ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Factors Not Significant for 1 Year Mortality Recipient Factors: IV inotropes, sternotomy, history of malignancy, hospitalized, diabetes Donor Factors: Gender, clinical infection, history of diabetes Transplant Factors: CMV mismatch, HLA mismatch, center volume

  38. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Age = <1 YearsRisk Factors For 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,009 Reference diagnosis = congenital without PGE or ECMO

  39. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Age = <1 YearsBorderline Significant Risk Factors For 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,009

  40. PEDIATRIC HEART TRANSPLANTS(1/1996-6/2008)Age = <1 Years Risk Factors for 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,009

  41. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year Mortality in Age = <1 YearsIschemia Time ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,009

  42. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year Mortality in Age = <1 YearsPre-TransplantCreatinine ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,009

  43. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year Mortality in Age = <1 YearsCenter Volume for Pediatric Transplants ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,009

  44. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year Mortality in Age = <1 YearsRecipient Height ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,009

  45. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Age = 1-10 YearsRisk Factors For 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,448 Reference diagnosis = cardiomyopathy

  46. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Age = 1-10 YearsBorderline Significant Risk Factors For 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,448

  47. PEDIATRIC HEART TRANSPLANTS(1/1996-6/2008)Age = 1-10 Years Risk Factors for 1 Year Mortality ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,448

  48. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year Mortality in Age = 1-10 YearsPre-TransplantCreatinine ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,448

  49. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year Mortality in Age = 1-10 YearsRecipient Height ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,448

  50. PEDIATRIC HEART TRANSPLANTS (1/1996-6/2008)Risk Factors for 1 Year Mortality in Age = 1-10 YearsRecipient Bilirubin ISHLT 2010 J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141 N=1,448

More Related