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HEART TRANSPLANTATION

HEART TRANSPLANTATION. Pediatric Recipients. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS (1982-2001). AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART RECIPIENTS (1982-2001). 385. 378. 372. 365. 363. 364. 349. 350. 356. 326. 340. 319. 254. 193. 130. 109. 75. 42. 11. 9.

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HEART TRANSPLANTATION

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  1. HEART TRANSPLANTATION Pediatric Recipients

  2. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS(1982-2001)

  3. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART RECIPIENTS(1982-2001)

  4. 385 378 372 365 363 364 349 350 356 326 340 319 254 193 130 109 75 42 11 9 AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTSBy Year of Transplant Number of Transplants * Numbers may be low due to delayed reporting.

  5. NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS * Numbers may be low due to delayed reporting

  6. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: < 1 Year)

  7. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS(Age: 1-10 Years)

  8. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS(Age: 11-17 Years)

  9. PEDIATRIC HEART TRANSPLANTATIONActuarial Survival (1982-2001) <1 year vs. 1-10 years: p = 0.0005 <1 year vs. 11-17 years: p = 0.001

  10. PEDIATRIC HEART TRANSPLANTATIONConditional Actuarial Survival(1982-2001) Both comparisons with 11-17 years significant at p < 0.0001

  11. PEDIATRIC HEART TRANSPLANTATIONConditional Actuarial Survival for Recent Era (1998-2001) Comparison of <1 vs. 11-17 years significant at p = 0.01

  12. PEDIATRIC HEART TRANSPLANTATIONActuarial Survival by Era (1982-2001) Survival (%) All comparisons with 1998-2001 are significant at p < 0.0001 Comparison of 1982-1987 vs. 1988-1992 was significant at p = 0.003 Comparison of 1982-1987 vs. 1993-1997 was significant at p < 0.0001

  13. PEDIATRIC HEART TRANSPLANTATION Actuarial Survival by Age GroupFor Diagnosis = Cardiomyopathy(1988-2001) Survival (%) No comparisons were statistically significant.

  14. PEDIATRIC HEART TRANSPLANTATION Actuarial Survival By Age GroupFor Diagnosis = Congenital Disease(1988-2001) Survival (%) Comparison of <1 vs. 11-17 was significant at p = 0.01

  15. PEDIATRIC HEART TRANSPLANTS (1996-2001)Risk Factors For 1 Year MortalityIn Descending Order of Magnitude N=1,554

  16. PEDIATRIC HEART TRANSPLANTS (1996-2001)Risk Factors for 1 Year MortalityContinuous Factors N=1,554

  17. PEDIATRIC HEART TRANSPLANTS (1996-2001) Factors Not Significant for 1 Year Mortality

  18. PEDIATRIC HEART TRANSPLANTS (April 1994 - December 1996)Risk Factors For 5 Year MortalityIn Descending Order of Magnitude N=937

  19. PEDIATRIC HEART TRANSPLANTS (April 1994 - December 1996)Risk Factors For 5 Year MortalityContinuous Factors N=937

  20. PEDIATRIC HEART TRANSPLANTS(April 1994 - December 1996)Factors Not Significant for 5 Year Mortality

  21. PEDIATRIC HEART TRANSPLANTS (April 1994 - December 1996)Risk Factors for 5 Year Mortality Conditional on Survival to 1 YearIn Descending Order of Magnitude N=728

  22. PEDIATRIC HEART RECIPIENTS Functional Status (April 1994-December 2001)

  23. PEDIATRIC HEART RECIPIENTS Rehospitalization Post-transplant(April 1994 - December 2001)

  24. PEDIATRIC HEART RECIPIENTSInduction ImmunosuppressionFor follow-ups between October 1999 and December 2001

  25. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Any Time During Follow-up PeriodFor follow-ups between October 1999 and December 2001

  26. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between October 1999 and December 2001

  27. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between October 1999 and December 2001 1 Year Follow-up (N=429) 5 Year Follow-up (N = 303)

  28. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between October 1999 and December 2001

  29. POST-HEART TRANSPLANT MORBIDITY FOR PEDIATRICSCumulative Incidence for Survivors(April 1994-December 2001)

  30. Freedom from CAV For Pediatric Heart Recipients(April 1994-December 2000)

  31. Freedom from Renal Dysfunction*For Pediatric Heart Recipients(April 1994-December 2000) * Renal dysfunction = Creatinine > 2.5 mg/dl, dialysis or renal transplant

  32. MALIGNANCY POST-HEART TRANSPLANTATION FOR PEDIATRICSCumulative Incidence for Survivors(April 1994-December 2001)

  33. Freedom from MalignancyFor Pediatric Heart Recipients(April 1994-December 2000)

  34. PEDIATRIC HEART TRANSPLANTATIONActuarial Survival Based on Prednisone Use p = 0.005

  35. PEDIATRIC HEART TRANSPLANTATIONActuarial Survival Based on Rejection within 1st Year P = 0.09

  36. PEDIATRIC HEART RECIPIENTSRelationship of Prednisone Use and CADTransplants: April 1994 – December 1999 p = 0.4 p = 0.06

  37. PEDIATRIC HEART RECIPIENTSRelationship of Rejection and CADTransplants: April 1994 – December 1999 p = 0.02 p = 0.09

  38. PEDIATRIC HEART RECIPIENTS Incidence of Hypertension between 1 and 3 Years

  39. PEDIATRIC HEART RECIPIENTS Incidence of Hypertension by 3 Years

  40. PEDIATRIC HEART RECIPIENTSGrowth Following Transplantation: HeightStratified by Prednisone Use at Discharge and at 1 Year

  41. PEDIATRIC HEART RECIPIENTSGrowth Following Transplantation: WeightStratified by Prednisone Use at Discharge and at 1 Year

  42. PEDIATRIC HEART RECIPIENTS: Time of Death(1988-2001)

  43. PEDIATRIC HEART TRANSPLANT RECIPIENTS: Cause of Death(1982-2001) Cause of Death (%) Timing of Death

  44. PEDIATRIC HEART TRANSPLANTS RECIPIENTS: CAUSE OF DEATH BY ERA: Deaths in 0-30 Days

  45. PEDIATRIC HEART TRANSPLANTS RECIPIENTS: CAUSE OF DEATH BY ERA: Deaths in 31 Days - 1 Year

  46. PEDIATRIC HEART TRANSPLANTS RECIPIENTS: CAUSE OF DEATH BY ERA: Deaths in >1 Year - 3 Years

  47. PEDIATRIC HEART TRANSPLANTS RECIPIENTS:CAUSE OF DEATH BY ERA: Deaths in >3 Years - 5 Years

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