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Essential Insights into Skeletal Muscle Stimulation and Neuromuscular Junction Anatomy

Explore the intricate workings of skeletal muscle stimulation, from the somatic motor neuron synapse to acetylcholine mechanisms, and delve into the detailed anatomy of the neuromuscular junction. Understand the structure of skeletal muscle at the molecular level and how neurotransmitter receptor mechanisms influence muscle function.

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Essential Insights into Skeletal Muscle Stimulation and Neuromuscular Junction Anatomy

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  1. Skeletal Muscle Stimulation and Anatomy • Somatic motor neuron synapse and function • Acetylcholine mechanisms of action and breakdown • Neurotransmitter receptor mechanisms • Skeletal muscle structure from the sarcomere molecular components to the whole muscle.

  2. Anatomy of the Neuromuscular Junction Somatic motor neuron Synapse Motor endplate of muscle fiber membrane

  3. A somatic motor neuron branches to multiple muscle fibers. One neuron + its target muscle fibers = a motor unit Enlarged axon terminal =bouton Somatic motor neuron axon Muscle fiber (cell)

  4. Skeletal Muscle Fiber (=single cell)

  5. Myofilaments Actin Muscle Fibres Myosin Myofilaments Muscle Fibers Myofibrils

  6. Sarcomere structure

  7. Scanning EM 1 5 4 2 3

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