1 / 19

Innovative Tissue Acquisition Tools for Gene Expression Analysis and Patient Comfort

This presentation by Prof. Jaak Ph. Janssens, MD, PhD, explores new tissue acquisition tools designed to enhance tissue quality and patient comfort in translational research. It emphasizes the importance of using large core soft tissue biopsy needles that ensure minimal pain and complication risk while yielding representative samples for molecular biology applications. The session outlines the double rota-cutting technique and the advantages of products like Spirotome, addressing various anatomical sites. Attendees will gain insights into improving tissue acquisition reliability for personalized therapy and prognostic marker analysis.

casta
Download Presentation

Innovative Tissue Acquisition Tools for Gene Expression Analysis and Patient Comfort

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. New tissue acquisition tools for gene expression analysis Tissue quality and patient comfort Prof. Jaak Ph. Janssens MD, PhD

  2. Translational Research • Molecular biology research • PCR, microchips, • Proteomics, genomics,… • Mutation research, polymorphisms • Screening • Risk biomarkers • Diagnosis • Fine tuning and reclassification • Personalized therapy • Prognostic markers • Pathway analysis – response prediction

  3. Obstacles for translational research

  4. Obstacles for translational research

  5. Requirements for tissue acquistion related to translational research • Tissue quality • Representative • One large piece of tissue • No artifacts • Patient comfort • No pain, no complication risk = safe • Inexpensive • Access • Handsome • Fast – minimal personnel • No dedicated room

  6. Tissue acquisition quality problem

  7. Fine needle aspiration (Cytology) • Microbiopsy (16 to 14 Gauge) • Macrobiopsy (8 to 12 Gauge) • Open biopsy (general anaesthesia)

  8. Results from safety and efficacy trials (n = 300 patients)

  9. Tissue acquisition for translational research

  10. Medinvents’ Products • A range of large core soft tissue biopsy needles • Based on NEW double rota-cutting technique • 8 – 14 Gauge • Vacuum system on Single Use • Product portfolio: • Spirotome Single Use/Reusable • Spirotome Cervicore ™ • Spirotome MRI ™ • Spirotome Bone ™ • Spirotome Easy Punch ™ • Automated version • Handheld or stereotactically positioned • Reusable handle controller, disposable • 8 – 10 Gauge needles • Vacuum assisted system • Multiple samples without reinserting

  11. Medinvents’ Applications • Spirotome™ • Breast • Thyroid • Salivary glands • Thoracic wall • Abdominal wall • Lymph nodes • Muscle • Liver • Coramate ™ • Breast • Thyroid • Salivary glands • Thoracic wall • Abdominal wall • Lymph nodes • Muscle • Spirotome Cervicore ™ • Cervix • Uterus • Spirotome Bone ™ • Soft tissues within bone • Spirotome Easy Punch ™ • Skin • Vulva

  12. Conclusion

  13. Clinical Study & Advisory Group Thank you.

More Related