Investigation of Cdc28 and APCCdh1 Activity on Cin8, Kip1, and Ase1 Stability and Bundling

DESCRIPTION

This study explores the roles of Cdc28, APCCdh1 (both active and inactive forms), and their impact on the stability of Cin8, Kip1, and Ase1 in budding yeast. By assessing the bundling activity of various protein complexes under different conditions, we aim to elucidate the mechanisms governing microtubule dynamics and stability. Unraveling these interactions will contribute to our understanding of cell cycle regulation and mitotic spindle formation, providing insights into essential cellular processes.

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May 18, 2026

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Investigation of Cdc28 and APCCdh1 Activity on Cin8, Kip1, and Ase1 Stability and Bundling

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