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High-Intensity Focused Ultrasound Therapy Array. May1005 Alex Apel Stephen Rashid Justin Robinson. Problem / Need Statement. Problem Traditional Tumor Removal: Invasive HIFU: Non-Invasive Tumor Removal Need Research tool to Control HIFU Therapy Array Independent Control of Transducers.

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high intensity focused ultrasound therapy array

High-Intensity Focused Ultrasound Therapy Array

May1005

Alex Apel

Stephen Rashid

Justin Robinson

problem need statement
Problem / Need Statement
  • Problem
    • Traditional Tumor Removal: Invasive
    • HIFU: Non-Invasive Tumor Removal
  • Need
    • Research tool to Control HIFU Therapy Array
    • Independent Control of Transducers
requirements wishes
Requirements & Wishes
  • Requirements
    • Generate Independent Waveform
      • 1.1 MHz
      • 500W Instantaneous Power
      • 0.01% - 1% Duty Cycle
  • Wishes
    • Collect Feedback Data
      • 50 M Samples / Sec
      • Provide Feedback Access
    • User Interface
      • Clean Interface to System
      • Specify waveform properties
        • Pulse Duty Cycle
        • Pulse Period
        • Pulse Count
      • Relative Phase
risks
Risks
  • Loss of Team Member
  • Damage to Equipment
  • Lack of Expertise
  • Time Constraints
  • Budget Constraints
software architecture
Software Architecture

RS-232

Micro

GUI

  • Input
  • Generate Waveform
  • Process Feedback
  • Input
  • Relative Transducer Phase
  • Transducer Amplitude
  • Signal Period
  • Signal Duty Cycle
  • Start/Stop Generation
  • Output
  • Phase

Control Logic

Transducer

Feedback

Analog Hardware

Transducer

Transducer

Transducer

software prototype architecture
Software Prototype Architecture

Micro

  • PWM
  • Two Channel Control
  • Hard Coded Waveform

Control Logic

Analog Hardware

Transducer

Transducer

Transducer

software implementation
Software Implementation
  • User Interface
    • Serial Communication with MCU
    • Graphical Input
  • Microcontroller
    • Prototype Implementation
      • PWM: Direct Control
    • Final Implementation
      • PreliminarySerial Communication
software testing evaluation
Software Testing & Evaluation
  • PC Software
    • Unit Testing of Serial Communication
    • Further Testing: On Hold
  • Microcontroller Software
    • Prototype Software
next steps
Next Steps
  • Two-way Communication: MCU PC Software
  • Fabrication of PCB
    • Writing Waveforms to RAM
    • Reading Feedback from RAM
digital architecture
Digital Architecture

MCU

Feedback RAM

Waveform RAM

Feedback RAM

Waveform RAM

ADC

Analog Circuitry

ADC

Analog Circuitry

digital implementation
Digital Implementation
  • Microcontroller
    • Acquisition Complete
    • Writing software
    • Paused for PCB Layout
  • Logic Circuitry
    • IC Acquisition Complete
    • Logical Layout Complete
    • PCB Layout Complete
    • PCB Routing in Progress
  • Prototype Software
    • Fully Implemented
    • Capable of bypassing Logic Circuitry
    • Critical for system prototype
digital testing evaluation
Digital Testing & Evaluation
  • Testing
    • Microcontroller
      • Test Code
      • Controls Waveform Directly
    • Logic Circuitry
      • Not Implemented
    • Prototype Software
      • Range of desired Waveforms
  • Evaluation
    • Microcontroller
      • System in place
      • Executes
    • Logic Circuitry
      • System ready for assembly
      • System easily modified
      • Bypassed
    • Prototype Software
      • Asserts Logic Circuitry Waveform
next steps1
Next Steps
  • Microcontroller
    • Complete Software
    • Use ribbon cable to physically connect to PCB
  • Logic Circuitry
    • Assemble the ordered PCB
    • Write and execute waveforms
    • Read back feedback data
    • Remove role of prototype code
analog implementation
Analog Implementation
  • H-Bridge
  • Half-Bridge
  • HIP4081A controller
analog architecture
Analog Architecture

Half Bridge A

Transducer

From Micro

Half-Bridge Controller

High Voltage DC

Power Supply

Transducer

Half Bridge B

analog testing evaluation
Analog Testing & Evaluation
  • Emulation testing
    • Problems
    • Potential
  • Low power transducer
  • High power transducer
next steps2
Next Steps
  • Further evaluation of half-bridge amplifier
  • Integration with logic circuitry
  • Expansion to more channels
  • Test with Transducer
lessons learned
Lessons Learned
  • Prioritize System Features from Beginning
  • Controlling System Scope is Important
  • Order Extra Parts
  • Hardware Takes a Long Time to Realize
  • Knowing Your Tools is Key to Development Time
  • Benefit from Others Experience
acknowledgments
Acknowledgments

Dr. Timothy Bigelow

Dr. Randy Geiger

Texas Instruments

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