1 / 7

Synthetic route

Explore the synthetic route to prepare Grignard reagents starting from basic substrates using various methods. This guide presents multiple sequences for creating effective Grignard reagents, evaluating the best electrophiles and reagents for the final step of synthesis. Each option is analyzed to determine the most viable pathway, ensuring successful formation of the desired product. Enhance your understanding of Grignard reactions and broaden your synthetic abilities with this informative resource.

callia
Download Presentation

Synthetic route

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Synthetic route To make: Start with: USING A GRIGNARD REACTION!

  2. Clickers: which sequence would be a workable route to the required Grignard reagent? A: B: C:

  3. Clickers: which sequence would be a workable route to the required Grignard reagent? A: B: C:

  4. Clickers: Which is the best electrophile to use?

  5. Clickers: Which is the best electrophile to use?

  6. Clickers: What reagent(s) would be best for the last step? A: KOtBu, tBuOH B: H2, Pd, MeOH C: H2SO4 (aq.) D: Zn(Hg), HCl

  7. Clickers: What reagent(s) would be best for the last step? A: KOtBu, tBuOH B: H2, Pd, MeOH C: H2SO4 (aq.) D: Zn(Hg), HCl

More Related