Foundation training in laboratory safety. Faculty Safety Managers: Jan de Abela-Borg and Stefan Hoyle. Training program. Module 1: Principles of laboratory safety (including bio safety) Module 2: Hazardous chemicals Module 3: Gases, cryogenics and other hazards Assessment MCQs.
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Faculty Safety Managers:
Jan de Abela-Borg and Stefan Hoyle
Images 2, 3, 4 & 5 were accidents that occurred at other organisations not Imperial College LondonWhat are we trying to prevent? Injuries.........................
Faculties and Depts
Something with the potential to cause harm
Identify the hazard
Identify who may be harmed
The likelihood and severity of harm occurring
Evaluate the risk and
identify control measures
Record the assessment
Review the assessment
Chemicals (incl toxins)
Any other substance hazardous to health inc wood dust, plant toxins, cleaning materials, oils and plenty more!)
1st fundamental principle – prevent exposure
Elimination – Don’t do it or;
Substitution - substituting ‘it’ with another substance which presents less, or no risk;
using another process which doesn’t create a hazardous form of that substance.
Segregation - If substitution is not possible then start by considering whether the work is adequately isolated from other staff, students, contractors or visitors.
All biological agents must be classified in one of four Hazard Groups
Lab containmentLevel 1
Increasing hazard to human health
High Efficiency Particulate
Exhaust HEPA filter
Do not have another worker at an adjacent bench
Allow adequate room for workers at nearby benches
Microbiological safety cabinet
Proper use: before you start workProper use: whilst at the cabinetProper use: after completion of the work
Main infection hazard is HIV, HepB and HepC
A) 1 + 3
What is GM?
Micro-organisms, plants and animals that have had their heritable genetic material altered by artificial means.
Gene of interest (insert)
e.g. bacterial expression system.....
Requires that all GMOs are classified in one of four Classes
Increasing hazard to human health or the environment
Classification of GMM determined by Containment Level required
All GM work must be assessed by the relevant GM Safety Committee BEFORE generation, use or storage of any GM material.
If you are using GM material – ALWAYS ask to see the associated GM assessment
If using Class 2 or 3 GM material you will need to be on Bio-agents health screening provided by College Occupational Health.
Also remind your supervisor that the GM Form C needs to be updated