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The Allergy Epidemic Dr Adam Fox Consultant in Paediatric Allergy Guy’s & St Thomas’ Hospital 16 October 2013. Ancient History. Modern History. Hay fever – Dr John Bostock first described in 1819 Based on his own symptoms Second paper on 28 cases - took 9 years to acquire.
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Dr Adam Fox
Consultant in Paediatric Allergy
Guy’s & St Thomas’ Hospital
16 October 2013
allos = "other"
ergon = "reaction"
An inappropriate, potentially harmful reaction by the immune system to a harmless stimulus.
Clemens Von Pirquet 1874-1929
Proportion of the children with asthma, suspected allergic rhinitis, eczema and oral-gastrointestinal symptoms in combination with other allergic manifestations n= 1417
at least 2
Wickman et al, Allergy 2004
40% of UK children have an allergic diagnosis
Gupta et al Clin Exp All 2005
3-4 will have eczema but 12 will have suffered at some point
3 or more children are likely to have asthma
4 or more children will be suffering from rhinitis
Juniper EF et al. Assessment of quality of life in adolescents with allergic rhinoconjunctivitis: development and testing of a questionnaire for clinical trials. J Allergy Clin Immunol. 1994 Feb;93(2):413-23.
Juniper EF et al. Measuring quality of life in children with rhinoconjunctivitis. J Allergy Clin Immunol. 1998 Feb;101(2 Pt 1):163-70.
Simons FE Learning impairment and allergic rhinitis.Allergy Asthma Proc. 1996 Jul-Aug;17(4):185-9
Walker S et al. Hayfever has a significant detrimental impact on national exam performance in UK teenagers: case control study. JACI 2007.
1-2 children are likely to have a food allergy (although 10 may think they have)
Venter C et al. Allergy. March 2008
Community cohort of 969 children born 2001-2
Cumulative incidence of FA was 5.0%
33.7% of parents reported a food related problem (only 12.9% of these confirmed)
Rates of Peanut Allergic in UK Paediatric Cohorts
27 adult & 20 Paediatric consultants identified in 2010 RCP report
No significant expansion planned
Est 2% of appropriate children receive IT (Vance. Clin Exp Allergy 2010)
2848 Australian infants SPT at 12months
Prevalence of food allergy 10.4%
Increasing pattern of disease
Relative lack of service provision