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Comparative Analysis of Bcl-xL and Mcl-1 Expression in Tumors

This study investigates the impact of Bcl-xL and Mcl-1 expression on tumor development and progression. The data presents insights into the role of these proteins in cancer biology.

bruce-wade
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Comparative Analysis of Bcl-xL and Mcl-1 Expression in Tumors

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  1. A Bcl-xL-/- Bcl-xL+/+ B Mcl-1-/- Mcl-1+/+ Supplementary Fig. 1

  2. A Bcl-xL-/-No.1 T1 Bcl-xL-/-No.3 T1 Bcl-xL+/+ Bcl-xL-/-No.1NT Bcl-xL-/-No.1 T2 Bcl-xL-/-No.2 NT Bcl-xL-/-No.2 T1 Bcl-xL-/-No.2 T2 Bcl-xL-/-No.2 T3 Bcl-xL-/-No.3NT Bcl-xL-/-No.4 NT Bcl-xL-/-No.4 T1 Bcl-xL-/-No.4 T2 Bcl-xL-/-No.4 T3 Bcl-xL-/-No.5 NT Bcl-xL-/-No.5 T1 Bcl-xL+/+ Bcl-xL+/+ Bcl-xL+/+ Beta actin Mcl-1 B Mcl-1-/-No 1 T1 Mcl-1-/-No 4 T1 Mcl-1-/-No 6 T1 Mcl-1+/+ Mcl-1-/-No.1 NT Mcl-1-/-No 2 NT Mcl-1-/-No 2 T1 Mcl-1-/-No 3 NT Mcl-1-/-No 3 T1 Mcl-1-/-No 3 T2 Mcl-1-/-No 3 T3 Mcl-1-/-No 3 T4 Mcl-1-/-No 4 NT Mcl-1-/-No 4 T2 Mcl-1-/-No 5 NT Mcl-1-/-No 5 T1 Mcl-1-/-No 5 T2 Mcl-1-/-No 5 T3 Mcl-1-/-No 6 NT Mcl-1-/-No 6 T2 Mcl-1+/+ Mcl-1+/+ Beta actin Bcl-xL Supplementary Fig.2

  3. Bcl-xL-/-Tumor Mcl-1-/-Tumor Supplementary Fig.3

  4. A Mcl-1-/- Mcl-1+/+ Bak+/+ Bak-/- Bak+/+ Bak-/- Ki67 B * * * Ki-67 positvenucli (-/-) (-/-) Bak (+/+) (+/+) Mcl-1+/+ Mcl-1-/- SupplementaryFig. 4

  5. * Sirius red stained area (%) (-/-) Bak (+/+) Mcl-1-/- Bak+/+Mcl-1-/- Bak-/-Mcl-1-/- SupplementaryFig. 5

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