1 / 21

Understanding Host-Parasite Interaction: The Role of Normal Flora and Pathogens

Delve into the intricate relationship between host and parasites, explore the impact of normal flora, pathogens, and infections on various body systems. Learn about key opportunistic pathogens, adaptation mechanisms, and virulence factors.

brownchad
Download Presentation

Understanding Host-Parasite Interaction: The Role of Normal Flora and Pathogens

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Host-Parasite Relationship • Normal Flora • Pathogens • Infections • Opportunistic • pathogens

  2. Skin Flora • 180 species • Streptococcus • Staphylococcus • Propionibacterium • Body Odor • Acne

  3. Oral Cavity Flora • Plaque • Anaerobes • Biofilms • Dental Caries • Streptococcus mutans, sobrinus • Sucrose

  4. Tongue

  5. Intestinal Tract Stomach – pH Helicobacter pylori • Small Intestine • Enterococci, • Lactobacilli

  6. Large intestine • 1010-1011 cells/gm • Bacteroides • Enterobacteria • Escherichia coli • Enterococcus

  7. Large Intestine Flora • Methanogens • Food passage 24 hrs • Excrete 1013/day • Probiotics • Fecal transplant

  8. Respiratory Tract • Staphylococcus aureus • Streptococcus pneumoniae • S. pyogenes • Corynebacterium diphtheriae • Carrier

  9. Urogenital Tract Opportunistic Pathogens E. coli Virulence Invasiveness Toxicity Lactobacillus acidophilus

  10. Adherence • Specific Adherence • Capsule • Slime Layer • Glycocalyx • Fimbriae • Pili - longer

  11. Invasiveness • Colonization Factor Antigen • Invasion • Colonization • Iron- Siderophore • Bacteremia vs. Septicemia

  12. Enzymes & Toxins • Coagulase • Collagenase • Exotoxins • Cytolytic Toxins • Hemolysins, Leukocidins • Diphtheria Toxin • Botulism Toxin • Tetanus Toxin Tetanus

  13. Other Toxins Enterotoxin Cholera toxin Endotoxin – Pyrogen LD50 Virulence Factors Attenuated Strains Pyrogen free Products

  14. Virulence Factors

  15. Nonspecific Host Defense • Natural Resistance • Age • Stress • Diet • Anatomical Defenses • Skin, Stomach, Tears

  16. Compromised Hosts Inflammation Fever Nosocomial Infections

  17. Host-Parasite Word List Stomach – pH2 Helicobacter pylori Small Intestine Enterococci, Lactobacilli Large Intestine 1010- 1011 cells/gram Normal Flora Pathogens Infection Skin Flora Staphylococcus, Propionibacterium Oral Cavity Flora Plaque Streptococcus spp Dental Caries Streptococcus mutans Intestinal Tract

  18. Host-Parasite Word List 2 1010- 1011 cells/gram Bacteroides, Enterobacteria, Escherichia coli, Enterococcus Respiratory Tract Staphylococcus aureus, Streptococcus pneumoniae, S. pyogenes,Corynebacterium diphtheriae Carrier Urogenital Tract Opportunistic Pathogens Virulence Invasiveness, Toxicity Specific Adherence

  19. Host-Parasite Word List 3 Capsule, Glycocalyx, Slime Layer Fimbriae, Pili Colonization Factor Antigen Enzymes & Toxins Coagulase, Collagenase Exotoxins Cytolytic Toxins Hemolysins, Leukocidins Invasion Colonization Iron – Siderophore Bacteremia – Septicemia

  20. Host-Parasite Word List 4 Endotoxin LD50 Attenuated Nonspecific Host Defenses Natural Resistance Natural Resistance Age, Stress, Diet Anatomical Defenses Skin, Stomach, Tears Diphtheria Toxin Botulism Toxin Tetanus Toxin Enterotoxin Cholera Toxin

  21. Host-Parasite Word List 5 Compromised Host Inflammation Fever

More Related