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Charles Pallandt Regional Director Turkey, Middle East and Africa

Catching up with other hospital consortia in the world. Tayfun Basal Sales Manager Turkey t.basal@elsevier.com Mob phone: 0 533 771 8689. Charles Pallandt Regional Director Turkey, Middle East and Africa. Agenda. Introduction: Health Science market analysis.

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Charles Pallandt Regional Director Turkey, Middle East and Africa

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  1. Catching up with other hospital consortia in the world Tayfun Basal Sales Manager Turkey t.basal@elsevier.com Mob phone: 0 533 771 8689 Charles Pallandt Regional Director Turkey, Middle East and Africa

  2. Agenda • Introduction: Health Science market analysis. • Current and future content on ScienceDirect: - Journals including Cell Press - Books • Xpharm • PharmaPendium

  3. Health Science Market Share 2006 by Publishers

  4. Elsevier – Market share (% papers published) in Health Science Harcourt acquisition Elsevier (3/4%) outperforms average market growth 2/3%)

  5. Health Science Summary by Publisher Influence (or Citation Share) - Indicates the share of citations that the publisher has. Citations have been measured over a five-year period (2001 -2005).

  6. The impact of electronic acces:Turkey; accelerated output after universities were on Science Direct Article output 1996-2005 Turkish CAGR (’00-’05) : 25% Source: Thomson Scientific (ISI)

  7. Handbooks 7 series Reference Works 51 titles Book Series 145 titles ~3 million articles 1995 - present Backfiles pre 1995 2000 journals ~4 million articles Content on ScienceDirect today

  8. Journals on ScienceDirect • Contains >2000 journals • Elsevier Science • Pergamon • North Holland • Academic Press • Harcourt Health Sciences • Cell Press • etc • > 7.9 million full-text articles • 23 subjects • Articles In Press • Backfile articles back to Volume 1, Issue 1

  9. All journals are available on ScienceDirect from volume 1, issue 1 The Lancet – vol 1, no. 1 - 1823.

  10. ScienceDirect Content – Cell Press • Cell Presspublishes prestigious highly-cited biomedical research journals Cell Neuron Immunity Molecular Cell Developmental Cell Cancer Cell Current Biology Structure Chemistry & Biology Cell Metabolism

  11. Cell • The 2004 Nobel Prize in Physiology/Medicine awarded to Richard Axel, M.D., and Linda S. Buck, Ph.D., for their work studying the organization of the olfactory system was based on research published in their seminal 1991 Cell paper.

  12. ScienceDirect Content – Cell Press Ground-breaking articles from the Cell Press journals are now available at the desktop. Discovery • 1984 Ubiquitin as central cellular regulator • 2003 Gene required for stem cell pluripotency Knowledge • 1979 Tyrosine phosphorylation • 1989 Rag1 mediates antibody diversity Impact • 1974 First cloning of eukaryotic gene • 1994 Mechanisms of long-term memory

  13. Cell Press: High-impact journals available at the desktop • Each Cell Press title is at or near the top of its ISI subject category. • Cell – with a current Impact Factor of 27.254 according to the 2002 ISI Journal Citation Report – has been the top research journal in the cell biology and biochemistry and molecular biology categories six of the last seven years. • Similar impressive statistics apply to Neuron and Immunity in their respective categories. Newer titles like Molecular Cell, Developmental Cell and Cancer Cell have quickly established themselves as top-tier journals within their respective communities.

  14. Book Series ScienceDirect Content – Online Books Reference Works/ Encyclopedia Handbooks (NEW) 7 packages163 titles 51 Titles 7 series 164 volumes

  15. Elsevier Book Series Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Now with over 400 volumes since 1955, the series contains much material still relevant today — truly an essential publication for researchers in all fields of life sciences. "The 'Methods in Enzymology' series represents the gold-standard."Neuroscience "Incomparably useful."Analytical Biochemistry "A series that has established itself as a definitive reference for biochemists."Journal of Chromatography

  16. Biomedical Method Research Title

  17. Elsevier Reference Works • High quality reference material. • Highly detailed and structured. • Highly used and cited. • 51 now available on ScienceDirect including: Encyclopedia of Cancer Encyclopedia of Endocrine Diseases Encyclopedia of Gastroenterology Encyclopedia of Hormones Encyclopedia of Human Nutrition Encyclopedia of Immunology Encyclopedia of the Neurological Sciences Encyclopedia of Toxicology Encyclopedia of Virology Encyclopedia of Biological Chemistry Meyler's Side effects on Drugs Encyclopedia of Genetics

  18. Elsevier Handbooks series • Launched 7 series in Chemistry, Mathematics, Physics and Economics in 2005. • Chapters by commissioning & invitation only. • Validated, refereed and edited by authoritative editors • Highly cited. • Usually long life cycle – up to 15 years. Forthcoming in 2006 Handbooks of Neurology

  19. Forthcoming in August 2007 Over 4000 eBooks!

  20. www.sciencedirect.com

  21. Find journals/books of interest.

  22. Find journals/books of interest. Option 2

  23. Find journals/books of interest

  24. Find journals/books of interest

  25. Find articles of interest

  26. Find journal of interest

  27. Find articles of interest

  28. Find articles of interest

  29. Searching – Quick search

  30. Searching – for more advanced features

  31. Searching

  32. Searching

  33. Example

  34. Example

  35. Usage statistics

  36. Overall ScienceDirect Usage 270 M 10 million regular users 36 full-text downloaded every second of a regular working day. 86 M 140 M 53 M 85 M

  37. Health Science Market Share 2006 by Publishers Science Direct usage is more than fair share!

  38. Usage statistics • Available via http://usagereports.elsevier.com (Password protected)

  39. xPharm A Pharmacological Reference Database for Life Scientists

  40. What is xPharm? An easily accessed, well thought through and highly functional repository of pharmacological information that quickly provides answers to in-depth pharmacology questions. Agents Targets Disorders Principles • And the mechanisms that govern their interaction “xPharm is an exceptional resource – a one of a kind undertaking that is an encyclopedia of modern pharmacology” Howard Gendelman, M.D. Chair, Department of Pharmacology University of Nebraska

  41. Easy to use • Consistent color coding to orient the user • Easy Browsing from table of Contents • Support for basic and advanced queries alzheimer

  42. Detailed xPharm displays more detailed information about pharmacologically relevant targets than any print and online source Classification and alternate names Pharmacological regulation Disease associations Assays

  43. Extensive & Comprehensive xPharm automatically links researchers to related sources of information • Genetic database • Protein database • Literature • Full-text articles • Additional supporting material, such as an ECG Library

  44. The Essential Drug Safety Resource

  45. PharmaPendium • A single source web based system that allows a single search to retrieve Preclinical animal, Human clinical trial and Post-market safety data, and intelligent pathways to that data.

  46. Who would find this useful? • Preclinical Safety Teams • Toxicologists • ‘Discovery’ Toxicologists • Safety Pharmacologists • DMPK, ADME • Medicinal Chemists • Clinical Researchers • Regulatory Affairs

  47. PharmaPendium: Sources • 3,000 Drugs covered • FDA Approval Packages • Preclinical, clinical • Meyler’s Side Effects of Drugs 15th Edition • Major reference work • Package Insert information (Labels) • Drug Monographs: Current & Withdrawn after 1997 • Toxicity/Metabolites extracted from literature. • Adverse Event Reporting System (AERS) • Post market • Drug/Target associations

  48. FDA Approval Package Database • US-approved drugs (1992 and later) • 1400+ drugs with approval documents • 700 with full Review sets (most 1992 and later); over 700 others with partial packages. • ~ 23,000 Documents • ~ 650,000 pages of information • ~ 300,000 extracted safety records • Preclinical & Clinical data extracted. • Full FDA reviews, label updates, warnings, etc. • Able to be navigated via text search, chemistry search, and browsed by target, drug, class.

  49. FDA Database: July Update • Update: • 9,800 new searchable documents • 204,000 new searchable pages. • After 1st Update: • 33,000 documents • 850,000 pages

  50. FDA Database: July Update Free evaluations to all presented products for the coming 6 weeks: 1. Journals / e-books on Science Direct 2. Cell Press 3. Xpharm 4. PharmaPendium

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