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Influence of HGF and EGF on c-Met Activation in A549 Cells

This study investigates the impact of Hepatocyte Growth Factor (HGF) and Epidermal Growth Factor (EGF) on c-Met activation in A549 cells. Results show increased c-Met phosphorylation upon HGF and EGF stimulation. Western blot analysis demonstrated changes in c-Met levels and downstream signaling. The study provides insights into the molecular mechanisms underlying growth factor-induced c-Met activation in lung cancer cells.

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Influence of HGF and EGF on c-Met Activation in A549 Cells

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  1. H1435 Vehicle HGF EGF pMet IP: c-Met c-Met c-Met b-Actin Figure S3 A549 Vehicle HGF EGF pMet IP: c-Met c-Met 1 2.8 9.2 1 2.1 7.5 c-Met Total Lysate Total Lysate b-Actin 1 1.3 1.5 1 1.1 1.8

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