the structure of the cell membrane n.
Skip this Video
Loading SlideShow in 5 Seconds..
The Structure of the Cell Membrane PowerPoint Presentation
Download Presentation
The Structure of the Cell Membrane

Loading in 2 Seconds...

play fullscreen
1 / 18

The Structure of the Cell Membrane - PowerPoint PPT Presentation

  • Uploaded on

The Structure of the Cell Membrane. The Structure of Membrane Lipids. Membrane-forming lipids contain both a polar, hydrophilic region and a nonpolar , hydrophobic region. Phospholipids are amphipathic :

I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
Download Presentation

PowerPoint Slideshow about 'The Structure of the Cell Membrane' - brice

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.

- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
the structure of the cell membrane
The Structure of the Cell Membrane
the structure of membrane lipids
The Structure of Membrane Lipids

Membrane-forming lipids contain both a polar, hydrophilic region and a nonpolar, hydrophobic region.

Phospholipids are amphipathic:

The “head” region, consisting of a glycerol, a phosphate, and a charged group, contains highly polar covalent bonds.

The “tail” region is comprised of two nonpolar fatty acid or isoprene chains.

When placed in solution, the phospholipid heads interact with water while the tails do not, allowing these lipids to form membranes.

phospholipid bilayers

Phospholipid bilayers form when two sheets of phospholipid molecules align. The hydrophilic heads in each layer face a surrounding solution, while the hydrophobic tails face one another inside the bilayer.

Phospholipid bilayers form spontaneously, with no outside input of energy required.

phospholipids and water
Phospholipids and Water

Phospholipids do not dissolve when they are placed in water.

Water molecules interact with the hydrophilic heads but not with the hydrophobic tails.

This drives the hydrophobic tails together.

Upon contact with water phospholipids form either:


Heads face the water and tails face each other.

Phospholipid bilayers (lipid bilayers)

selective permeability of lipid bilayers
Selective Permeability of Lipid Bilayers

The permeability of a structure is its tendency to allow a given substance to pass across it.

Phospholipid bilayers have selective permeability.

Small or nonpolar molecules move across phospholipid bilayers quickly.

Charged or large polar substances cross slowly, if at all.

many factors affect membrane permeability
Many Factors Affect Membrane Permeability

Many factors influence the behavior of the membrane:

Number of double bonds between the carbons in the phospholipid’s hydrophobic tail

Length of the tail

Number of cholesterol molecules in the membrane


bond saturation and membrane permeability
Bond Saturation and Membrane Permeability

Double bonds between carbons in a hydrocarbon chain can cause a “kink” in the hydrocarbon chain, preventing the close packing of hydrocarbon tails, and reducing hydrophobic interactions.

Unsaturated hydrocarbon chains have at least one double bond.

Hydrocarbon chains without double bonds are termed saturated.

Saturated fats have more chemical energy than unsaturated fats.

Membranes with unsaturated phospholipid tails are much more permeable than those formed by phospholipids with saturated tails.

other factors that affect permeability
Other Factors That Affect Permeability
  • Hydrophobic interactions become stronger as saturated hydrocarbon tails increase in length.
    • Membranes containing phospholipids with longer tails have reduced permeability.
  • Adding cholesterol to membranes increases the density of the hydrophobic section.
    • Cholesterol decreases membrane permeability.
  • Membrane fluidity decreases with temperature because molecules in the bilayer move more slowly.
    • Decreased membrane fluidity causes decreased permeability.
fluidity of the membrane
Fluidity of the Membrane
  • Individual phospholipids can move laterally throughout the lipid bilayer.
    • They rarely flip between layers.
  • How quickly molecules move within and across membranes is a function of temperature and the structure of the hydrocarbon tails in the bilayer.
You want to construct a molecule that will migrate easily through a cell membrane. What properties should you give your molecule?

Review Questions

a. It should be small and charged.

b. It should be large and hydrophilic.

c. It should be hydrophobic.

d. It should be hydrophilic.

which of the following events would you expect to be spontaneous in aqueous water solutions
Which of the following events would you expect to be spontaneous in aqueous (water) solutions?

a. net movement of calcium ions from 1.5 molar CaCl2 to 2.0 molar CaCl2

b. net movement of sugar molecules from 0.5 molar sugar to 0.4 molar sugar

c. net movement of water from a 1.2-molar solution of NaCl to a 0.9-molar solution of NaCl

d. net movement of water from 0.3 molar sugar to pure water

Yeast cells require a protein to transport glucose from the environment into the cell. You would expect that protein to be _____.

a. a transmembrane (integral) protein

b. a peripheral membrane protein

c. present only in the cytoplasm

d. an ion channel