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The Muscular System. Part II Skeletal Muscle Contraction. Introduction. Muscles receive… Actin and myosin… Sarcomeres… Muscle fibers… Pulls on…. Fig. 9.8. Neuromuscular Junction. Each skeletal muscle fiber ___________ connected to a neuron Neurons (Motor Neurons) 1. 2. 3.

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The Muscular System


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the muscular system

The Muscular System

Part II

Skeletal Muscle Contraction

introduction
Introduction
  • Muscles receive…
  • Actin and myosin…
  • Sarcomeres…
  • Muscle fibers…
  • Pulls on…
neuromuscular junction
Neuromuscular Junction
  • Each skeletal muscle fiber ___________ connected to a neuron
  • Neurons (Motor Neurons)

1.

2.

3.

  • Neurotransmitters

1.

2.

3.

4.

neuromuscular junction1
Neuromuscular Junction
  • Synapse

1.

2.

  • Ach receptors

1.

2.

stimulus for contraction
Stimulus for Contraction
  • Muscle impulse

1.

2.

excitation contraction coupling
Excitation Contraction Coupling
  • Muscle impulse causes …
  • Ca2+ binds to …
  • Binding sites …
  • Actin can…
the sliding filament theory
The Sliding Filament Theory
  • Sarcomeres…
  • Thin and thick filaments …
  • Slide past one another

1.

2.

3.

cross bridge cycling
Cross-Bridge Cycling
  • Sarcomere shortening

1.

2.

3.

  • ATP is required

1.

2.

  • Cross- bridge binding repeats

1.

2.

relaxation
Relaxation
  • Nerve impulse…
  • Acetylcholinesterase

1.

2.

  • Calcium …
  • Myosin…
  • Tropomyosin …

*ATP …

    • Rigor mortis
diseases of the muscular system
Diseases of the Muscular System
  • Polio

1.

2.

  • Botulism

1.

2.

clin app 9 1 myasthenia gravis
Clin. App. 9.1: Myasthenia Gravis

1.

2.

3. Symptoms

a.

b.

4. Treatment

a.

b.

c.

d.