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CELL MEMBRANE. I. Functions: Selectively Permeable - controls which substances pass into and out of cell. Site of important metabolic reactions. Outpouchings & infoldings increase surface area. CELL MEMBRANE. II. Structure: Composed mainly of lipids & proteins. Fluid Mosaic Model –
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CELL MEMBRANE I. Functions: • Selectively Permeable - controls which substances pass into and out of cell. • Site of important metabolic reactions. • Outpouchings & infoldings increase surface area.
CELL MEMBRANE II. Structure: • Composed mainly of lipids & proteins. • Fluid Mosaic Model – 1. behaves more like a fluid than a solid. 2. lipids & proteins can move so their pattern (mosaic) changes.
CELL MEMBRANE • Bilayer of phospholipids 1. Heads a. Hydrophilic - "water loving" b. Attracted to H2O c. Orient toward surfaces close to H2O
CELL MEMBRANE 2. Tails a. Hydrophobic - "water fearing" b. Repelled by H2O c. Orient away from surface toward inner portion of membrane d. Lipid soluble/ water insoluble
CELL MEMBRANE 3. Both sides of cell membrane are surrounded by water. This causes the phospholipids to form two layers: a. Hydrophilic heads point outward. b. Hydrophobic tails point inward
CELL MEMBRANE • This lipid bilayer structure is important in the membrane's function of being selectively permeable. • (only allows fat-soluble substances through)
Proteins in Plasma Membrane Peripheral Integral Globular Fibrous
CELL MEMBRANE • Proteins 1. Peripheral proteins a. located on surface (interior or exterior) b. Help cell to change shape (phagocytosis)
CELL MEMBRANE 2. Integral proteins • embedded in the lipid bilayer. • some have carbohydrates attached which may be receptor sites for chemicals or viruses. • some form channels, pores, or 'shuttles' that allow substances to pass through.
CELL MEMBRANE a. Fibrous: • tightly coiled & rodlike • may span from cell's inside to outside • communicate between opposite ends • specialized receptors to hormones
CELL MEMBRANE b. Globular: • compact • span the membrane • form channels specific for certain ions & molecules • form pores that allow water through
CELL MEMBRANE • (Proteins help to make cell membrane selectively permeable. They allow non-fat solubles to pass through)
CELL MEMBRANE • Cholesterol Molecules 1. embedded in interior of membrane 2. give stability to membrane
Plasma Membrane Animation • http://www.wiley.com/legacy/college/boyer/0470003790/animations/membrane_transport/membrane_transport.htm