EVIDENCE FROM GENETICS
This comprehensive guide explores monohybrid and dihybrid crosses, key concepts in genetics. By analyzing examples, including crosses between homozygous recessive and heterozygous traits, the material helps clarify dominant and recessive inheritance patterns. Discover the implications of Gregor Mendel's experiments with pea plants, learn to calculate offspring ratios, and delve into the principles of independent assortment. Enhance your understanding of genetic principles while answering interactive questions related to real-world scenarios in inheritance.
EVIDENCE FROM GENETICS
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Presentation Transcript
Can you answer this? Which represents a monohybrid cross between a homozygous recessive and a heterozygote? A) Tt x Tt B) ttmm x TtMm C) tt x Tt D) ttmm x TTMM
Can you answer this? In rats, black fur is dominant over white. If a white rat is crossed with a heterozygous black rat, what is the likely % of the offspring that will be white? • 0% • 25% • 50% • 75%
And can you answer this? Which of the following pairs of crosses results in the same phenotypic ratios? • Aa x Aa and AA x aa • AA x aa and AA x Aa • AA x Aa and Aa x aa • None of the above
EVIDENCE FROM GENETICS • Deduction: If the hypothesis of evolution is correct, then we should see evidence of this in genetics • Background: Gregor Mendel (1822-1884 Experiments with the garden pea. His paper in 1866 established the field of genetics.
Monohybrid Crosses(=Breeding experiments involving one trait) • Pea plants • P Tall x Tall Short x Short • F1 All Tall All Short
Monohybrid Crosses(=Breeding experiments involving one trait) • Pea plants • P Tall x Tall Short x Short • F1 All Tall All Short • F2 All Tall The tall trait is dominant
Monohybrid Crosses(=Breeding experiments involving one trait) • Pea plants • P Tall x Tall Short x Short • F1 All Tall All Short • F2 F2 x F2 All Tall
Monohybrid Crosses(=Breeding experiments involving one trait) • Pea plants • P Tall x Tall Short x Short • F1 All Tall All Short • F2 F2 x F2 • F3 75% Tall, 25% Short All Tall 3:1 Ratio
5474/1850= 2.96 6022/2001= 3.01 882/299= 2.95 428/152= 2.82 705/224= 3.15 651/207= 3.14 787/277= 2.84 MENDEL’S TRAITS
5474/1850= 2.96 6022/2001= 3.01 882/299= 2.95 428/152= 2.82 705/224= 3.15 651/207= 3.14 787/277= 2.84 MENDEL’S TRAITS 3:1 Ratio
Mendel analyzes the data Traits passed in the gametes Pollen (sperm) & eggs Note: ¾ Tall= TT, Tt, tT ¼ Short= tt 3:1 Phenotypic Ratio
Terms and Principles • Dominant (e.g. Tall) • Recessive (e.g. Short) • Phenotype (visible characteristics) • Genotype (genetic characteristics) • Particulate theory of inheritance= 2 particles (factors) determine a trait Blending hypothesis is wrong!
Using a Punnett Square Alleles= Alternative forms of the same gene (T or t) T t T TT Tt t Tt tt Suppose Tt X Tt
Using a Punnett Square Note: 3:1 ratio Eggs T t T TT Tt Pollen t Tt tt Tall Tall Short Tall
Using a Punnett Square Homozygous condition= both alleles are alike (TT or tt) T t T TT Tt t Tt tt
Using a Punnett Square Heterozygous condition= both alleles are different (Tt) T t T TT Tt t Tt tt
Clicker Question • Blue eyes (b) are recessive to brown (B).Suppose 2 parents had 11 children: 6 with blue and 5 with brown. Which of these statements is most likely to be right? • Both parents had blue eyes. • One parent had blue & the other was homozygous dominant • Both parents had brown eyes. • One parent had blue & the other was heterozygous • Both parents were heterozygous.
Dihybrid Crosses(=Breeding experiments involving two traits) Round (R) or Wrinkled (r) seeds Yellow (Y) or Green (y) seeds P RRYY x rryy F1 RrYy Genotype Round Yellow Phenotype
Dihybrid Cross RrYy x RrYy Set up a Punnet Square
Dihybrid Cross RrYy x RrYy Fill in this line first
Dihybrid CrossRrYy x RrYy Now fill in the rest
Clicker QuestionWhat belongs in the red square? • A) RRYY • B) RrYY • C rrYy • D) rrYY • E) rryy
Clicker Question:How many wrinkled green seeds will there be out of 16 possibilities? • A) All 16 • B) 9 out of 16 • C) 50% • D) 3 0ut of 16 • E) 1 out of 16
Clicker Question:How many wrinkled green seeds will there be out of 16 possibilities? • A) All 16 • B) 9 out of 16 • C) 50% • D) 3 0ut of 16 • E) 1 out of 16
Dihybrid CrossRrYy x RrYy 9: 3: 3: 1 Round Round Wrinkled Wrinkled Yellow Green Yellow Green
Principle of Independent Assortment = Factors (genes) sort independently of one another. i.e. all possible combinations of Y and y and R and r occur BUT
What ifRY are linked together & ry are linked together ? Non Independent Assortment
Can you answer this? Which represents a monohybrid cross between a homozygous recessive and a heterozygote? A) Tt x Tt B) ttmm x TtMm C) tt x Tt D) ttmm x TTMM
Can you answer this? In rats, black fur is dominant over white. If a white rat is crossed with a heterozygous black rat, what is the likely % of the offspring that will be white? • 0% • 25% • 50% • 75%
And can you answer this? Which of the following pairs of crosses results in the same phenotypic ratios? • Aa x Aa and AA x aa • AA x aa and AA x Aa • AA x Aa and Aa x aa • None of the above
According to J.K. Rowling wizards & witches can be born from pure bloods or muggles. Suppose the wizard/witch trait is recessive (m)and the muggle trait is dominant (M) • Hermione is a witch born of muggle parents. If her parents had another child what are the chances that that one also would be a wizard or witch? • 0% • 25% • 50% • 75% • 100% B E D A C