Quantitative Imaging: Protocol Development and Quality Assurance Issues for Medical Imaging in Clinical Trials H. Cecil Charles, Ph.D. Director Duke Image Analysis Laboratory Duke University Medical Center Overview Quantitative Imaging vs: Clinical Imaging Protocol Development Issues
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H. Cecil Charles, Ph.D.
Duke Image Analysis Laboratory
Duke University Medical Center
Visualization of lesions and/or disease From Clinical Imaging (CI)?
Rule-out or rule-in a diagnosis
Diagnostic tree/1°,2°,3° diagnosis
Determination of tissue characteristics from imaging parameters
Incorporation in hypothesis testing or goal driven evaluationCI QI
Organ volumes or Subvolumes From Clinical Imaging (CI)?
Metabolic Indices (e.g. pH, energetics)
Vascular IndicesExamples of QI