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SPERMATOGENESIS

SPERMATOGENESIS. Dr.Hardijanto.,MS.,Drh Dr. Suherni Susilowati.,MKes,Drh Tatik Hernawati., MSi.,Drh Trilas Sardjito.,MSi., Drh Tri Wahyu Suprayogi., MSi., Drh. SPERMATOGENESIS.

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SPERMATOGENESIS

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  1. SPERMATOGENESIS Dr.Hardijanto.,MS.,Drh Dr. Suherni Susilowati.,MKes,Drh Tatik Hernawati., MSi.,Drh Trilas Sardjito.,MSi., Drh Tri Wahyu Suprayogi., MSi., Drh

  2. SPERMATOGENESIS • Definition : spermatogenesis is a process forming of spermatozoa from germ cells (spermatogonium/spermatogonia) that happened in seminiferous tubules of the testis • There are two process of spermatogenesis - 1) spermatocytogenesis - 2) spermiogenesis

  3. Cont’ • In the seminiferous tubules is composed of two basic cell types that is: the sertoli cells and the developing germ cells. • The germ cells undergo a continous series of celluler divisions and developing changes, beginning at the periphery and progressing toward the lumen of the tubule. • The steam cells, called spermatogonia, divide several times before forming spermatocytes

  4. Cont’ SPERMATOCYTONESESIS • - spermatogonium spermatocyte I spermatocyte II spermatid . SPERMIOGENESIS .- spermatid are transformed into spermatozoa. The spermatid then undergo a progressive series of structural and developmental changes to form spermatozoa Spermatogenesis process consist of mitosis and meiosis divisions. During spermatogenesis, the function of sertoli cells to give energy for developing germinal cells.

  5. ENDOCRINE CONTROL OF SPERMATOGENESIS .- Normal testicular function requires hormonal stimulation by gonadotropins, which are turn controlled by pulsatile secretion gonadotropin releasing hormone (GnRH) from the hypothalamus - And then GnRH stimulates the secretion of LH and FSH from the anterior pituitary • The LH stimulated the interstitial cells of Leydig to produce androgen mainly tetosteron.

  6. The function of FSH is for maintenance of spermatogenesis • Testosteron is secreted into seminiferous tubule, where it is necessary for maintenance of spermatogenesis and also secreted into the bloodstream , where they cause the development of secondary sex characteristics of the male and development and maintenance of the reproduction tract.

  7. Cont’ • The FSH interacts with receptors on the Sertoli cells to cause production of androgen binding protein (ABP), conversion of testosterone to dehydrotestosteron and estrogen, stimulation of spermatocytogenesis and secretion of inhibin. • The inhibin secreted into the bloodstream has a negatif feedback effect on FSH but not on LH secretion.

  8. SPERMATOGENESIS mitosis (15 – 17 hari) Spermatogonium (2n) Sp A Sp B Sp A Sp B Spermatocyte I (2n) Spermatocyte II (n) Spermatocyte II (n) Spermatid Spermatid Spermatid Spermatid (n) (n) (n) (n) Spermatozoa Spermatozoa Spermatozoa Spermatozoa Meiosis (30 – 32 hari) Meiosis ( 31– 32 hari) Metamorfosa (40 – 47 hari)

  9. Sperm Morphology • Sperm Head :- The major feature is the oval, flattened nucleus containing highly compact chromatin----- DNA (haploid) • -The anterior end of the sperm nucleus is cover by acrosome. At acrosome there are hyaluronidase, acrosine and corona penetrating enzyme----is involved in the fertilization process. • Sperm Tail : Composed of neck,middle,principle and end piece

  10. Plasma membrane Head Middle Piece Posterior Nucleus Membrane b. Head Mitocondria Membrane Central distal (centriol ring) 9 Outer Fibril Principle piece 9 inner double fibril tail 2 Midlle Fibril c. Middle Piece Tail Membrane 9 double fibril End piece 2 Middle Fibril d. Principle Piece a. General view

  11. Normal Sperm Microcephalic Macrocephalic Short widely head Head of piryformis Double head double tail Narrow head length Middle shares swell Circle of tail Attachment of abaxial

  12. Spermatozoa Abnormal • Divided two: - Primer Abnormal - Second Abnormal • Covering : - Abnormal at head - Abnormal at tail

  13. Accessories gland • Function : - giving energi - movement medium - neutralize of reproduction channel • A great deal of semen dilution • Many carbohydrate, protein, amino acid, enzyme, dissolve vitamin in water, mineral, citric acid, Na, K, Ca, Mg • Compose : - Seminalis Vesicularis gland - Prostate gland - Bulbourethralis / couper’s gland

  14. Con’t • Prostate gland : Dog, cat • Seminalis vesicularis and Bulbourethralis gland : Ox Sheep, goat, horse, buffalo, pig • This function of gland is influenced testosteron

  15. Structure of Duties • 1.Explaining process forming of sperm at livestock • 2. Explaining endocrine controle on spermatogenesis • 3.Mentioning the part of sperm and its function • 4. Explaining the function of the accessories glands in each species

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