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Gregg H. Gilbert, DDS, MBA, FAAHD, FACD for the CONDOR Collaborative Group

The dental practice-based research network as a potential platform for future research. Gregg H. Gilbert, DDS, MBA, FAAHD, FACD for the CONDOR Collaborative Group Network Chair of “DPBRN” Professor and Chair, Department of Diagnostic Sciences

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Gregg H. Gilbert, DDS, MBA, FAAHD, FACD for the CONDOR Collaborative Group

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  1. The dental practice-based research network as a potential platform for future research Gregg H. Gilbert, DDS, MBA, FAAHD, FACD for the CONDOR Collaborative Group Network Chair of “DPBRN” Professor and Chair, Department of Diagnostic Sciences University of Alabama at Birmingham School of Dentistry Monday, February 23, 2009 Neurosciences Center Building National Institute on Drug Abuse Rockville, MD Support: U.S. National Institutes of Health grants U01-DE-16746 and U01-DE-16747

  2. What is a dental practice-based research network (PBRN)? A group of dental practices that has affiliated to investigate research questions and to engage in sharing experiences and expertise.

  3. What is a dental practice-based research network (PBRN)? A group of dental practices that has affiliated to investigate research questions and to engage in sharing experiences and expertise. The network conducts research that is done by and about the “real world” of daily clinical practice, where the overwhelming majority of the population receives its dental care. Designed to gather “real-world” evidence for the prevention and treatment of oral diseases.

  4. How is PBRN research different from other types of research? Laboratory Clinical Practice-based Community- research trials research based in academic research settings

  5. The NIDCR dental PBRN initiative –key purposes • Answer questions facing general dental practitioners in the routine care of their patients • Strengthen knowledge base for making clinical • decisions • Establish/use a flexible, adaptable electronic network/platform for connectivity, data sharing, & communication within and between • dental and medical networks

  6. The NIDCR dental PBRN initiative –key purposes • Many questions faced by dentistry are most appropriately addressed in practice-based dental settings • Study power is increased by the potentially large number of both practitioners and study subjects

  7. CONDOR: a collaborative of three NIDCR-funded networks • DPBRN: based at UAB • NWPRECEDENT: based at UW, OHSU • PEARL: based at NYU • Collaborate on: • infrastructure issues • some research projects • data standardization and curation

  8. Three-Network Organization CONDOR organization National Monitoring Committee NIDCR CONDOR DSMB DPBRN CONDOR Directors Committee CONDOR Informatics Committee NWPRECEDENT CONDOR Publications Committee PEARL CONDOR PIRG

  9. Geographic areas currently covered by the CONDOR PBRNs

  10. Participating practitioners (n ≈ 600) after Year 04 • Alabama • Florida • Georgia • Mississippi • Minnesota • Oregon • Washington • Scandinavia Sweden Denmark Norway • Connecticut • Delaware • Maryland • Massachusetts • Michigan • New Hampshire • New Jersey • New York • Ohio • Pennsylvania • Rhode Island • Virginia • Vermont • Washington, D.C. • Idaho • Utah • Montana • Washington • Oregon

  11. Basic organizational structure of the individual CONDOR PBRNs • Network Chair group • Coordinating Center group • Executive Committee • NIDCR staff • Protocol Review Committee • IRBs • DSMBs and OSOCs • NIDCR PBRN Monitoring Committee

  12. Basic organizational structure of the individual CONDOR PBRNs • Network Chair group • Coordinating Center group • Executive Committee • NIDCR staff • Protocol Review Committee • IRBs • DSMBs and OSOCs • NIDCR PBRN Monitoring Committee • Let’s discuss one of these PBRNs as an example …

  13. DPBRN: a network about, with, and for practitioner-investigators Practical science done about, in, and for the benefit of “real world" clinical practice.

  14. The DPBRN regions

  15. DPBRN organization Executive Committee Protocol Review Committee NC/CC AL/MS Steering Committee Regional Coordination Group FL/GA MN Study Teams PDA Publications and Presentations Committee SK

  16. The DPBRN Executive Committee • The main decision-making body of the network • Majority voting authority lies with the six practitioner- investigator representatives

  17. The DPBRN Executive Committee AL/MS Dr. Gerald Anderson Selma, AL HP/MN Dr. Pat Foy Minneapolis, MN member-at-large for combined AL/MS, FL/GA region Dr. Martha Wallace Birmingham, AL PDA Dr. Dan Pihlstrom Portland, OR SK Dr. Lotta Persson Tyringe, Sweden FL/GA Dr. Paul Benjamin Miami, FL

  18. How many DPBRN members are there? Practitioners enrolled in DPBRN:* • 1,207 who completed an Enrollment Questionnaire • 565 completed an “Assessment of Caries Diagnosis and Caries Treatment Questionnaire” (only restorative dentists eligible) • 425 completed orientation training • 344 completed training in human participants research • 272 have completed one or more clinical studies • Includes general dentists, dental specialists, and dental hygienists. • * as of October 7, 2008

  19. Number of units in 9 DPBRN studies to date

  20. Annual regional meetings of practitioners DPBRN network-wide meeting May 15-17, 2008 Intercontinental Hotel Atlanta, GA

  21. web sites of the three dental PBRNs

  22. Thank you!

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