Colon Cancer. Elshami Elamin, MD Medical oncologist central care cancer center www.cccaner.com wichita , ks - usa. COLORECTAL CANCER. >140,000 new cases each yr in the US 3 rd leading cause of death It is curable if detected early. HNPCC (Lynch syndrome). Lynch I:
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T2 (invade muscul propria) B1
into subserosa or nonperit. Tissue)
T4 (perforate ves perit or B3
invade adjacent structure)
N3 (along vascular trunk)
With proven efficacy and a favourable safety profile, XELOX is a new standard of care in the adjuvant treatment of early colon cancer
T3 & MMR-D
T3 & MMR-P
T4 & MMR-P
Van Cutsem E, et al. ECCO/ESMO 2009. Abstract P-6077.
1. Tournigand C, et al. J Clin Oncol. 2004;22:229-237.
2. Cassidy J, et al. J Clin Oncol. 2008;26:2006-2012.
Recommends active chemo for total of 6 months of perioperative time